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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 61 (1990), S. 213-218 
    ISSN: 1432-0584
    Keywords: T-cell leukemia ; γ/δ receptor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Leukemic cells of a 20 year old patient, suffering from acute lymphoblastic leukemia, were characterized by surface marker and functional analysis. A significant cell population within this type of leukemia expresses concomitantly the CD4 and CD8 antigen on the same cell and might represent a new differentiation stage of T-cells with the γ/δ receptor. The leukemic cells show a distinct pattern of growth response to mitogens and lymphokines, which might correlate to their differentiation stage. Moreover, a “natural killer”-like activity can be induced in these cells by IL-2.
    Type of Medium: Electronic Resource
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