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Digitale Medien

Nitrosation of mefenorex in the presence of cyclodextrins (1987)

Frömming, K. -H. ; Wedelich, V. ; Mehnert, W.

Springer

Journal of inclusion phenomena and macrocyclic chemistry 5 (1987), S. 625-629

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Details

ISSN: 1573-1111

Schlagwort(e): Nitrosation reactions ; α-, β-, γ-cyclodextrin, dimethyl-β-cyclodextrin ; mefenorex ; nitrosomefenorex

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie

Notizen: Abstract β- and γ-Cyclodextrin (CD) and heptakis-2,6-di-O-methyl-β-cyclodextrin (DIMEB) form soluble inclusion compounds with mefenorex (MEF); with α-CD a partial inclusion occurs. No solid inclusion compound could be obtained with the four CDs. β-, γ-CD and DIMEB, but not α-CD, enhance the nitrosation rate of MEF if the nitrosation assay procedure (NAP test) is applied. During this reaction with β- and γ-CD, solid inclusion compounds of the CDs and nitrosomefenorex (NMEF) precipitate.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00663003

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