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Digitale Medien

Δ9-tetrahydrocannabinol induced inhibition of predatory aggression in the rat (1973)

Kilbey, M. Marlyne ; Moore, J. Will ; Hall, Margaret

Springer

Psychopharmacology 31 (1973), S. 157-166

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Details

ISSN: 1432-2072

Schlagwort(e): Δ 9-tetrahydrocannabinol ; Predatory Aggression ; Rat ; Serotonin

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract Δ 9-tetrahydrocannabinol inhibits predatory aggression in rats. Increases in the degree of inhibition are obtained with increasing dosages of the drug. Although sex and strain of the subjects varied nonsystematically, inhibition of predatory aggression uniformly was found to be dose related. Readministration of Δ 9-tetrahydrocannabinol did not effect motor activity measures at dose levels which inhibit aggression. Administration of Δ 9-tetrahydrocannabinol increases whole brain serotonin, while norepinepherine is largely unaffected, indicating that the anti-aggressive effect may be mediated, in part, by serotonergic mechanisms.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00419815

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