ISSN:
0138-4988
Keywords:
Life Sciences
;
Life Sciences (general)
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Process Engineering, Biotechnology, Nutrition Technology
Notes:
The new synthesis of 9α-hydroxy-4-androsten-3,17-dione from hydrocortisone is described. The six-step reaction sequence involved degradation of the side chain, dehydration, ketals formation, reduction of the α-epoxide to 9α-hydroxyderivative and ketal groups cleavage. The overall yield is about 12%. Physico-chemical data of two new compounds were determined.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/abio.370090510