ISSN:
0003-276X
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
The Kurloff body of guinea pig mononuclear leukocytes was studied by light and electron microscopy of blood and spleen. Electron microscopy disclosed the presence of extensively dilatedendoplasmic reticulum, clusters of small vesicles, and clumps of long parallel fibers in the cytoplasm. The osmiophilic inclusions contained many myelin figures, both around the periphery and free in the matrix. Evidence for motility of these cells was noted.Rods, filaments, and spheres seen in supravital preparations appear as myelin figures when seen with the electron microscope. Although historically considered, parasitism, nuclear extrusion and phagocytosis of cells are unlikely as causal in the formation of the inclusion. Being based on contradictable evidence, a lysosomal origin is doubted. The formative process isfelt to be either one of intracellular secretion or of a sequestering and concentration of a serum molecular component.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ar.1091560113
