ISSN:
0003-276X
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
Light microscopy of semithin sections revealed an increase in blood vessel profiles between one and three weeks postnatal. Ultrastructurally, at birth, there were few patent vessels, but endothelial cells enclosing a slit-like lumen were numerous. The endothelial cells contained a high concentration of free ribosomes and pinocytotic vesicles. Pseudopod projections of the endothelial cells into the vascular lumen were often present. The nuclei were very irregular and dense with clumped chromatin. The basal lamina varied in thickness. During the period between one and three weeks the nuclei of endothelial cells became less dense; the lumen became patent and the endothelial wall progressively thinner. The periphery of the vessel became completely surrounded by glial end feet and the basal lamina was regular and prominent. By three weeks, most blood vessels resembled blood vessels observed in a mature animal. Pericytes were present at all stages of development. The extracellular space which was quite conspicuous at birth was greatly reduced by the third week.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ar.1091780404