ISSN:
0075-4617
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
A Novel Synthesis of AntamanidBy cyclization of the linear decapeptide phenylalanyl-phenylalanyl-prolyl -prolyl-phenyl-alanyl-phenylalanyl-valyl-prolyl-prolyl-alanine (position 5 → 4 in formula 1,) with the help of dicyclohexylcarbodiimide/N-hydroxy-succinimide (DCC/HOSu) antamanid (1,) is obtained in a 36.5% yield.
Notes:
Durch Ringschluß des linearen Decapeptids Phe-Phe-Pro-Pro-Phe-Phe-Val-Pro-Pro-Ala (Stellung 5 → 4 in Formel 1) mittels Dicyclohexylcarbodiimid/N-Hydroxy-succinimid wird das cyclische Decapeptid Antamanid in 36.5 proz. Ausbeute erhalten.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.19697270115
