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Lithium lowers renal, cardiac and splenic ornithine decarboxylase activity in mice (1986)

Adlercreutz, C. ; Rosengren, E. ; Uvelius, B.

Springer

Cellular and molecular life sciences 42 (1986), S. 409-409

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ISSN: 1420-9071

Keywords: Lithium ; ornithine decarboxylase activity ; polyamines

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary A single i.p. injection of lithium chloride (5–7.5 μmoles/g b.wt) in mice caused a 70–80% decrease in renal, cardiac and splenic ornithine decarboxylase (ODC) activity within 1 h, whereas pulmonary ODC activity was unaffected. Lithium chloride did not have any effect on ODC activity in vitro when added to homogenates of the tissues studied. We suggest that the effect of lithium on ODC activity is not direct, but mediated via e.g. hormonal or nervous influence.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02118632

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