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The kinetic disposition and dosage regimen for carbenicillin in buffalo calves (1989)

Bal, M. S. ; Brar, K. S.

Springer

Veterinary research communications 13 (1989), S. 389-394

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ISSN: 1573-7446

Keywords: buffalo ; carbenicillin ; pharmacokinetics ; therapeutics

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract The distribution half-life, elimination half-life, apparent volume of distribution and total body clearance of carbenicillin in healthy buffalo calves following a single intravenous administration (50 mg/kg) were 0.057±0.005 h, 1.688±0.11 h, 0.185±0.021 L kg-1 and 75.97±6.519 ml kg-1 h-1 respectively. A satisfactory dosage regimen for carbenicillin in buffalo calves was calculated to be 56 mg/kg followed by 52 mg/kg body weight repeated at 6 h intervals.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00346071

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