ISSN:
1432-1440
Keywords:
Arteriosclerosis
;
Protein turnover
;
Cell turnover
;
15N Tracertechnical investigations
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The incorporation of the stable isotope15N in plasma proteins and blood cells after oral application of 3 g15NH4Cl (95 At%15N) per 70 kg body weight was followed up in 11 patients with ischemic heart disease or peripheral arteriosclerosis and in 7 healthy control subjects. Preliminary results indicate that the turnover of plasma protein, especially fibrin, is elevated in patients with arteriosclerosis. Investigations of platelets intimate a decreased turnover of platelet protein in patients with arteriosclerosis as compared to control subjects. Possible reasons for these alterations are discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01648246