ISSN:
1432-0428
Keywords:
Sodium-potassium-ATPase
;
dorsal root ganglia
;
streptozotocin diabetes
;
diabetic neuropathy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Sodium-potassium-ATPase activity was measured in excised dorsal root ganglia of streptozotocin-diabetic rats, 2 months after induction of diabetes. In comparison with agematched controls, there was a decrease in both the total and ouabain-insensitive activity, indicating an overall reduction in ouabain-sensitive activity of 46%. This decrease may explain the reduced amino-acid uptake exhibited by diabetic sensory ganglia and could be relevant to the development of diabetic neuropathy.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00279925