ISSN:
1432-072X
Keywords:
Aerobacter aerogenes
;
Glyphosate
;
5-Enolpyruvyl-shikimic acid-3-phosphate synthase
;
Resistance
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract The broadspectrum herbicide glyphosate (N-[phosphonomethyl]glycine), an inhibitor of the shikimate pathway enzyme 5-enolpyruvyl-shikimic acid-3-phosphate (EPSP)-synthase, inhibits the growth of Aerobacter aerogenes and causes the excretion of shikimic acid-3-phosphate. A strain of A. aerogenes, resistant to inhibition of growth by glyphosate, was isolated and found to have a glyphosate-insensitive EPSP-synthase and to no longer excrete shikimic acid-3-phosphate in the presence of glyphosate. Partial identity of EPSP-synthases from the glyphosate-sensitive and-resistant A. aerogenes strains was demonstrated by immunological procedures.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00414451
