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Digitale Medien

Fate of isosorbide dinitrate and mononitrates in patients with renal failure (1981)

Bogaert, M. G. ; Rosseel, M. T. ; Boelaert, J. ; [weitere]

Springer

European journal of clinical pharmacology 21 (1981), S. 73-76

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Details

ISSN: 1432-1041

Schlagwort(e): nitrates ; renal failure ; isosorbide dinitrate ; isosorbide 2-mononitrate ; isosorbide 5-mononitrate ; plasma concentrations

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie , Medizin

Notizen: Summary Isosorbide dinitrate 10 mg, isosorbide 5-mononitrate 5 mg and isosorbide 2-mononitrate 5 mg were administered orally to subjects with and without renal failure, and the plasma concentrations of isosorbide dinitrate and of both the mononitrates were measured. There was no striking difference in plasma concentration as a function of time between subjects with and without renal failure, except for a somewhat higher isosorbide 5-mononitrate concentration after administration of this metabolite to uraemic patients.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00609591

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