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Digitale Medien

In vitro effect of Fansimef on human neutrophil and monocyte function (1986)

Kharazmi, A. ; Nielsen, H.

Springer

European journal of clinical pharmacology 29 (1986), S. 587-590

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Details

ISSN: 1432-1041

Schlagwort(e): Fansimef ; phagocytosis ; malaria treatment ; neutrophil function ; monocyte function ; chemotaxis ; oxidative metabolism

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie , Medizin

Notizen: Summary The effect of Fansimef, a recently registered triple combination of mefloquine, sulfadoxine and pyrimethamine (10:25:1) on human peripheral blood polymorphonuclear and mononuclear leucocyte function was studied. At clinically obtainable concentrations Fansimef had no effect on leucocyte viability, it did inhibit neutrophil chemiluminescence and it had no effect on other major functions, such as chemotaxis, NBT reduction, superoxide production, phagocytosis and the bactericidal activity of phagocytic cells.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00635897

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