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Ultrastructural characterisation of macrophages (type A cells) in the synovial lining (1988)

Mapp, P. I. ; Revell, P. A.

Springer

Rheumatology international 8 (1988), S. 171-176

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ISSN: 1437-160X

Keywords: Ultrastructure ; Synovium ; Macrophages ; Immunoelectron microscopy

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The ultrastructural localisation of class II and macrophage antigens has been sought in the intimal layer of the human synovium. The cells described as type A in early morphological studies are shown to express both class II antigens and two markers of the macrophage/monocyte lineage of cells, OKM1 and MAB 24. The morphological type B cells were found to express none of these antigens. The findings are consistent with the idea that the synovial lining comprises two cell types, bone-marrow derived macrophages and mesenchymal fibroblasts.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00270456

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