ISSN:
1432-0533
Keywords:
Epithelial membrane antigen
;
Pacinian corpuscles
;
Perineurial cells
;
Perineurioma
;
Neurothekeoma
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Paraffin-embedded surgical pathology specimens from skin (5) and muscle (2) biopsies, from Morton's neuromas (3), traumatic neuromas (8), schwannomas (21), neurofibromas (12), and from one perineurioma and one neurothekeoma were studied by immunoperoxidase histochemistry and antibodies against epithelial membrane antigen (EMA), Leu 7 epitopes (Leu 7), S-100 protein (S-100) and cytokeratins. Normal, reactive and neoplastic perineurial cells stain consistently for EMA, whereas Schwann cells express Leu 7 and/or S-100 positivity. None of the immunoreactive cells stained for cytokeratin. Our findings indicate that perineurial and Schwann cells can easily be distinguished by their different patterns of immunoreactivity with the above markers.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00687077
