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  • 1
    Electronic Resource
    Electronic Resource
    Phenytoin elimination kinetics in two children with drug intoxication (1980)
    Springer
    European journal of pediatrics 135 (1980), S. 69-71 
    Details
    ISSN: 1432-1076
    Keywords: Phenytoin toxicity ; Michaelis-Menten kinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two girls aged 6 and 10 years treated with anticonvulsants developed nystagmus and ataxia. The peak plasma concentrations of phenytoin were 42.6 and 46.6 μg/ml, respectively, compatible with phenytoin toxicity. The decline in plasma phenytoin levels did not fit first order kinetics, but followed Michaelis-Menten kinetics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00445896
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