ISSN:
1432-0878
Schlagwort(e):
Kidney tubules
;
Zonulae occludentes
;
Gap junctions
;
Freeze-fracture
;
Electron microscopy
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary Intercellular junctions between human kidney tubular cells were studied by the freeze-fracture technique. The number of strands of the zonulae occludentes increased gradually from the proximal segment to the collecting tubule. Only one strand was visible in the proximal segment (in contrast to 2–4 strands of the neighbouring Bowman's capsule). In the thin segment 2–4 strands were revealed. In the distal segment 1–5 strands were present in the pars recta, 4–6 in the pars convoluta. The most extensive and complex zonulae occludentes were found in the collecting tubule. Gap junctions were seen only between proximal tubular cells. The extent of the zonulae occludentes along the tubules in human kidney is very similar to that observed in the kidney tubules of other mammals. The findings accord well with electrophysiological measurements and with the results of tracer studies on experimental animals.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00220577
