ISSN:
1432-0878
Keywords:
Peripolar cells
;
Juxtaglomerular apparatus
;
Newborn sheep
;
Dexamethasone
;
Ultrastructure
;
Cytoplasmic granules
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary In the renal juxtaglomerular region of newborn sheep, it was found that glomerular peripolar cells and their granules were very much larger than those found in fetal lambs or adult sheep. Similar peripolar cell hypertrophy was triggered in fetal lambs treated in utero with intraperitoneal injections of dexamethasone. Ultrastructurally, granules of peripolar cells from newborn lambs resembled closely the enlarged zymogen granules described in the pancreas of newborn rats. Such peripolar cell hypertrophy may reflect a functional adaptation of the kidney to immediate postnatal life.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00216531
