ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Since a small globular particle was first used as support for three-dimensional (3D) growth ofanchorage-dependent cells in suspended cultures, a variety of microspheres as tissue engineeringscaffolds have been developed. In this paper, β-TCP and chitosan were selected as the components ofmicrospheres due to their biodegradability and osteogenic properties. The biodegradable β-TCP/chitosancomposite microspheres were prepared by a solid-in-water-in-oil (s/w/o) emulsion cross-linking methodin this paper. The size distribution, surface morphology, and microstructure of the microspheres wereevaluated. Scanning electron microscopy revealed that the size of the microspheres with good sphericalmorphology was distributed in the range of 50~200μm. In vitro immersion experiments were carried outto evaluate the degradability of the microspheres, and the results demonstrated that the chitosan/β-TCPcomposite microspheres were potential materials as tissue engineering scaffolds for bone repair
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/53/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.336-338.1646.pdf
