Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Journal of neurochemistry
30 (1978), S. 0
ISSN:
1471-4159
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Abstract— Uptake of [3,5S]taurine by rat whole brain synaptosomes was studied at varying temperatures, under O2, and N2 atmospheres, during electrical stimulation and in the presence of dinitrophenol or variable taurine concentrations in the incubation medium. The morphology and purity of the synaptosomes was checked by electron microscopy. The respiration of the synaptosomes was linear for at least 90 min. The taurine uptake was energy- and temperature-dependent and significantly enhanced by electrical stimulation. The total uptake of taurine could be divided into three components, non-saturable influx and saturable high-affinity (Km= 46 μmol/l) and low-affinity (Km, = 6.3 mmol/l) transport systems. The efficacy of the high-affinity transport appears small in view of the postulated neurotrans-mitter role of taurine.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1471-4159.1978.tb10459.x
| Library |
Location |
Call Number |
Volume/Issue/Year |
Availability |
