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Digitale Medien

Vaccine strategies against Epstein-Barr virus-associated diseases: lessons from studies on cytotoxic T-cell-mediated immune regulation (1999)

Khanna, Rajiv ; Moss, Denis J. ; Burrows, Scott R.

Oxford, UK : Blackwell Publishing Ltd

Immunological reviews 170 (1999), S. 0

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Details

ISSN: 1600-065X

Quelle: Blackwell Publishing Journal Backfiles 1879-2005

Thema: Medizin

Notizen: Summary: Development of a vaccine against Epstein-Barr virus (HBV) is constrained by the latency phenotypes adopted by different EBV-associated diseases. Over the last few years an immense body of information on the pattern of viral gene expression in EBV-associated diseases and the rote of cytotoxic T cells in the control of these diseases has accumulated. It would seem reasonable to suggest that emerging technologies are at a level where vaccine trials aimed at controlling infectious mononucleosis, post-transplant lymphoproliferative disease, nasopharyngeal carcinoma and Hodgkln's disease are justified. On the other hand, a more cautious approach may be required for the development of vaccines or immunotherapeutic strategies against Burkitt's lymphoma.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1111/j.1600-065X.1999.tb01328.x

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