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  • Articles: DFG German National Licenses  (10)
  • 2000-2004  (10)
  • 2000  (10)
  • 1
    Electronic Resource
    Electronic Resource
    Fabrication of nanometric zinc pattern with photodissociated gas-phase diethylzinc by optical near field (2000)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 76 (2000), S. 2173-2175 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: In situ patterning of zinc on a nanometric scale has been accomplished by photodissociation of gas-phase diethylzinc by optical near field. By using an ultraviolet optical fiber probe with an aperture diameter of 60 nm, dots with full width at half maxima of 60 and 70 nm were deposited, and were separated by 100 nm. The aspect ratio of the dots increased at the rate of 0.03/μJ, as the optical near field energy increased. A T-shape pattern was also fabricated by scanning the probe in an optical near field microscope system. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.126288
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Angio-oedema in a neonate with IgG antibodies to parvovirus B19 following intrauterine parvovirus B19 infection (2000)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 143 (2000), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report a neonate with angio-oedema following fetal hydrops caused by maternal parvovirus B19 infection. Levels of complement components, including total haemolytic complement activity and C1 inhibitor concentration, were within normal ranges in cord blood. Neonatal angio-oedema might be included in the clinical spectrum of parvovirus B19 infection in pregnancy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2000.03676.x
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  • 3
    Electronic Resource
    Electronic Resource
    Deodorization of Fish Sauce by Continuous-Flow Extraction with Microbubbles of Supercritical Carbon Dioxide (2000)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 65 (2000), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Volatiles were removed from fish sauce by continuous-flow extraction with microbubbles of supercritical carbon dioxide. The extraction was done at 35 °C and CO2/sample flow ratio of 0.14 and 0.29 under pressures of 10 to 30 MPa. After the treatment at a CO2/sample flow ratio, 0.29 at 10 MPa, remaining percentage ((the concentration in treated sample/that in untreated one) × 100) was 5.2% trimethylamine, 8.0% S-methyl ethanethioate, 30% dimethyldisulfide, 55 to 61% aliphatic aldehydes, and 25 to 42% carboxylic acids. The increase in CO2 flow rate improved the extraction efficiency significantly, but no effect of pressure was observed. The odor intensities of treated samples were between 1/4 and 1/8 of the untreated fish sauce.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.2000.tb10610.x
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  • 4
    Electronic Resource
    Electronic Resource
    Development of systemic sclerosis in a patient with systemic lupus erythematosus and topoisomerase I antibody (2000)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 142 (2000), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We describe a patient with systemic lupus erythematosus (SLE) associated with topoisomerase I (topo I, Scl-70) antibody, a specific marker for systemic sclerosis (SSc). SSc patients who produce this antibody have severe cutaneous and visceral involvement, and eventually have a poor prognosis. It is rare to find this antibody in patients with other collagen diseases. Only four SLE patients have been reported in the English language literature who were topo I antibody-positive but had no clinical evidence of scleroderma. The serum of our patient with SLE had precipitating topo I antibody from the onset of his disease. Twelve years after the onset of SLE, he developed proximal scleroderma and pulmonary fibrosis. This case reconfirms the prognostic significance of topo I antibody as a predictive marker, and indicates that SLE patients with topo I antibody require careful follow-up for future development of scleroderma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2000.03492.x
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  • 5
    Electronic Resource
    Electronic Resource
    Fatal cerebral hemorrhage associated with cyclosporin-A/FK506-related encephalopathy after allogeneic bone marrow transplantation (2000)
    Springer
    Annals of hematology 79 (2000), S. 588-592 
    Details
    ISSN: 1432-0584
    Keywords: Key words Bone marrow transplantation ; Cerebral hemorrhage ; Cyclosporin A ; Encephalopathy ; FK506
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  We report a case of cerebral hemorrhage associated with cyclosporin A (CsA)/FK506-related encephalopathy that developed in a 16-year-old woman after allogeneic bone marrow transplantation. Hematopoietic engraftment occurred on day 15, and the patient developed systemic convulsions after CsA was replaced by FK506 for the treatment of acute graft-versus-host disease (GVHD). Based on magnetic resonance imaging, laboratory findings and cerebrospinal fluid studies, she was diagnosed as having CsA/FK506-related encephalopathy with cerebral hemorrhagic infarction. Although she recovered completely after discontinuation of FK506, she developed convulsions again 15 days after re-administration of FK506. A computed tomography scan showed cerebral hemorrhage. She died of respiratory failure. Vascular damage induced by immunosuppressive drugs and enhanced by acute GVHD seemed to be the cause of the cerebral hemorrhage. Since hypertension, which was present during both of the central nervous system events, seemed to have contributed to the development of the cerebral hemorrhage, it is proposed that CsA and FK506 should be reduced or discontinued when patients who have risk factors of hypertension become hypertensive even if they have no symptoms of neurotoxicity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002770000192
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  • 6
    Electronic Resource
    Electronic Resource
    19F NMR study of protein-induced rhombic perturbations on the electronic structure of the active site of myoglobin (2000)
    Springer
    JBIC 5 (2000), S. 455-462 
    Details
    ISSN: 1432-1327
    Keywords: Key words Fluorine-19 nuclear magnetic resonance ; Heme electronic structure ; Myoglobin ; Paramagnetic shift ; Reconstituted protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract  A novel C 2-symmetric ring-fluorinated hemin, 13,17-bis(2-carboxyethyl)-2,8,12,18-tetramethyl-3,7-difluoroporphyrinatoiron(III), has been synthesized and was incorporated into sperm whale apomyoglobin to investigate protein-induced rhombic perturbations on the electronic structure of the active site of myoglobin (Mb) using 19F NMR spectroscopy. NMR signals for 19F atoms introduced as substituents on the present heme in ferrous low-spin and high-spin and ferric low-spin complexes have been observed and their shifts sharply reflect not only the electronic nature of the heme iron, but also in-plane asymmetry of the heme electronic structure. The two-fold symmetric electronic structure of the ring-fluorinated hemin is clearly manifested in the 19F and 1H NMR spectra of its dicyano complex. The chemical equivalence of the two fluorine atoms of the heme is removed in the active site of myoglobin and the splitting of the two 19F NMR signals provides a quantitative probe for characterizing the rhombic perturbation of the heme electronic structure induced by the heme-protein interaction. The in-plane asymmetry of heme electronic structures in carbonmonoxy and deoxy Mbs have been analyzed for the first time on the basis of the shift difference between the two 19F NMR signals of the heme and is interpreted in terms of iron-ligand binding and/or the orbital ground state of the heme. A potential utility of 19F NMR, combined with the use of a symmetric fluorinated hemin, in characterizing the heme electronic structure of myoglobin in a variety of iron oxidation, spin, and ligation states, is presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007750050005
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  • 7
    Electronic Resource
    Electronic Resource
    Magnet designs for a crystal-lattice quantum computer (2000)
    Springer
    Applied physics 71 (2000), S. 11-17 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 03.67.Lx; 76.60.Pc; 85.70.w
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. A quantum computer using nuclear spins in a crystal lattice requires a method for addressing individual quantum bits. This identification can be achieved with a spatially varying magnetic field. Spins at different lattice sites can have distinguishable Zeeman frequencies allowing initialization, logic operations, and measurements to be performed through radio frequency (rf) pulse techniques. Here, we present magnet designs that have gradients between 1 and 20 T/μm, which are necessary to realize quantum computation with particular crystals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390050018
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  • 8
    Electronic Resource
    Electronic Resource
    Decoherence in crystal lattice quantum computation (2000)
    Springer
    Applied physics 71 (2000), S. 27-36 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 03.67.Lx; 76.60.Es; 75.30.Ds
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. Nuclear magnetic resonance (NMR) quantum computation in a crystal lattice holds more promise for scalability than its solution NMR counterpart, but dephasing is a severe concern. Pulse sequence refocusing can help bring the qubit dephasing time closer to the limit of the intrinsic decoherence time, but the intrinsic transverse relaxation time (T2) and the longitudinal relaxation time (T1) of the crystal must be sufficiently long for a successful implementation. We discuss these time scales and their relation to parameters relevant to quantum computation for several crystal types, discussing in detail the examples of CaF2, MnF2, and CeP. Included in the calculation of coherence times for CeP is the development of spin-wave spectra in a type-1 antiferromagnetic FCC lattice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390050021
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  • 9
    Electronic Resource
    Electronic Resource
    Studies on the binding mechanism of fluoroquinolones to melanin (2000)
    Springer
    Journal of infection and chemotherapy 6 (2000), S. 72-76 
    Details
    ISSN: 1437-7780
    Keywords: Key words Ocular melanin ; Melanin affinity ; Fluoroquinolones ; Metal ions ; Binding mechanism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to elucidate the binding mechanism of melanin and fluoroquinolones (ofloxacin, norfloxacin, ciprofloxacin, lomefloxacin, levofloxacin), we investigated the interaction of fluoroquinolones with compounds such as l-β-(3,4-dihydroxyphenyl) alanine (l-DOPA), l-tyrosine, 5-hydroxy-l-tryptophan, l-tryptophan, and l-phenylalanine, which possess the kind of functional groups that melanin does and are closely related to melanin. The recovery of drugs from the melanin-drug complexes by metal ions of Li, Na, Ka, Mg, Ca, Ba, Cu, Ni, and Fe was demonstrated. Smaller and highly charged cations were found to be more effective for this recovery, and magnesium ions were the most effective of all the ions investigated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00012154
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  • 10
    Electronic Resource
    Electronic Resource
    Characterization of a bovine herpesvirus type 4 isolated from the spinal cord of a cow with astasia (2000)
    Springer
    Archives of virology 145 (2000), S. 2363-2370 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary.  A bovine herpesvirus (BHV) strain designated B11-41, was recently isolated from the spinal cord of a cow with astasia. By BHV type specific polymerase chain reaction (PCR), a BHV-4 specific fragment was amplified from the DNA of strain B11-41. The nucleotide sequence of the PCR product revealed high homologies (98.4% and 99.8%) with those of two BHV-4 strains (Movar 33/63 and 86-068). The BamHI restriction endonuclease cleavage patterns of the B11-41 were more similar to those of BHV-4 than those of other types of BHV. BHV-4 is divided into two groups, European and American. The EcoRI, and BamHI, and HindIII restriction endonuclease analysis demonstrated that strain B11-41 was closely related to the American type of BHV-4. It was concluded that B11-41 was identified as a BHV-4 that belongs to the American group. Additionally, the results of this study may indicate that the nervous system is one of the sites of viral latency in natural infection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007050070026
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