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  • Articles: DFG German National Licenses  (50)
  • 1990-1994  (20)
  • 1985-1989  (30)
  • 1
    Electronic Resource
    Electronic Resource
    The effect of position and delay on stroke and minute distance in late pregnancy (1987)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 94 (1987), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Stroke and minute distance were measured in 12 women in late pregnancy using Doppler ultrasound. In each patient two sets of measurements were made every 2 min for 20 min in the supine and left lateral positions, the sequence of positions being reversed on the second occasion. Within each of the four 20 min measurement periods there were no significant changes with time in stroke distance, heart rate, or minute distance, or in their coefficients of variation. From this evidence there is no justification for delaying the measurement of cardiac output until a 'steady state’is reached. The measurements were influenced both by the sequence and the position in which they were taken, the effects being additive. Overall, stroke distance was 5·1% greater in the left lateral than in the supine position, heart rate was 3·7% less and minute distance not significantly different. Independent of posture, stroke distance was 6·5% greater in the second period of measurement than in the first, heart rate was 3% less and minute distance 2·8% more. In late pregnancy the relative magnitude of cardiac output in the left lateral and supine positions has to be interpreted in the light of a stepwise increase of aortic blood flow with change of posture.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1987.tb03141.x
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  • 2
    Electronic Resource
    Electronic Resource
    Oligonucleotides containing flexible nucleoside analogs (1990)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 112 (1990), S. 453-455 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00157a073
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Building blocks for oligonucleotide analogs with dimethylene sulfide, sulfoxide, and sulfone groups replacing phosphodiester linkages (1991)
    s.l. : American Chemical Society
    The @journal of organic chemistry 56 (1991), S. 3869-3882 
    Details
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jo00012a018
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  • 4
    Electronic Resource
    Electronic Resource
    ESTIMATING SEA OTTER REPRODUCTIVE RATES (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Marine mammal science 10 (1994), S. 0 
    Details
    ISSN: 1748-7692
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract: Sea otters may give birth in any month of the year, so obtaining reproductive rates by observation is difficult. Reproductive rates may be estimated directly (births per otter-year observed) or by determining the time interval between births. Both methods give the same result for long sequences of observations, but field data are limited to shorter periods. Monte Carlo simulations were conducted to compare the two approaches, and showed that the interval method overestimates true reproductive rates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1748-7692.1994.tb00387.x
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  • 5
    Electronic Resource
    Electronic Resource
    Effect of pressure on the insertion kinetics of metal-carbene complexes (1992)
    s.l. : American Chemical Society
    Organometallics 11 (1992), S. 267-269 
    Details
    ISSN: 1520-6041
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/om00037a048
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  • 6
    Electronic Resource
    Electronic Resource
    NEUROLOGICAL CONSEQUENCES OF MAGNESIUM DEFICIENCY: CORRELATIONS WITH EPILEPSY (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 14 (1987), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: SUMMARY1. The plasma calcium and magnesium concentrations of sheep have been manipulated by feeding liquid diets with various calcium and magnesium concentrations.2. When the magnesium status of the diet was low, both plasma calcium and magnesium concentrations declined, but the decline in calcium was much more rapid and extensive when the content of calcium in the diet was also low. This loss of calcium control in magnesium deficiency was attributed to end-organ resistance to parathyroid hormone.3. Correlation between plasma and CSF calcium and magnesium concentrations indicated that convulsions occurred when CSF magnesium and plasma calcium concentrations declined.4. The neurological mechanisms likely to be responsible for the induction of these convulsions are discussed and the factors precipitating convulsions in magnesium deficiency and epilepsy are compared.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1987.tb00985.x
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  • 7
    Electronic Resource
    Electronic Resource
    Topological structure of integral manifolds and period-doubling bifurcation (1987)
    Springer
    Zeitschrift für angewandte Mathematik und Physik 38 (1987), S. 302-314 
    Details
    ISSN: 1420-9039
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Description / Table of Contents: Zusammenfassung Wir untersuchen die topologische Struktur von Integralmannigfaltigkeiten in der Nähe einer geschlossenen Lösungskurve eines autonomen Differentialgleichungssystems. Wir beweisen, daß unter gewissen Umständen diese Mannigfaltigkeiten homöomorph zu einem Möbius-Band sind. Es wird gezeigt, daß das Auftreten einer Periodenverdopplungsbifurkation in parameterabhängigen Systemen eng mit der Existenz einer Zentrumsmannigfaltigkeit verknüpft ist, die homöomorph zu einem Möbius-Band ist. Abschließend demonstrieren wir, daß die Periodenverdopplungsbifurkation als Hopf-Bifurkation auf einem Möbius-Band behandelt werden kann.
    Notes: Abstract We investigate the topological structure of integral manifolds near a closed orbit of an autonomous differential system. We prove that under some circumstances these manifolds are homeomorphic to a Möbius strip. It is shown that the appearance of a period-doubling bifurcation in systems depending on a parameter is intimately connected with the occurence of a center manifold homeomorphic to a Möbius strip. Finally we demonstate that the period-doubling bifurcation can be treated as Hopf bifurcation on a Möbius strip.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00945415
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  • 8
    Electronic Resource
    Electronic Resource
    Computer optimization of the performance of an anaerobic filter used for purification of highly polluted wastewater from a sugar refinery (1989)
    Springer
    Cellular and molecular life sciences 45 (1989), S. 1024-1029 
    Details
    ISSN: 1420-9071
    Keywords: Anaerobic filter ; computer control ; optimization ; sugar refinery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary An anaerobic filter system with a volume of 11 l fed with wastewater from the Swiss sugar refinery in Frauenfeld was established on a laboratory scale. It provided a filter performance of over 8 kg COD·m−3·d−1 with an efficiency of at least 70%. A 600–1 pilot plant system in the factory gave a degradation efficiency of 70% when fed with 28 kg COD·m−3·d−1 and yielded 0.34 m3 methane/kg COD, demonstrating that the scaling-up of the anaerobic filter had been successful. The rapidly-varying concentrations of organic materials in the wasterwater required the constant control of the wastewater flow to the system. A control program was developed for a small computer using an empirical model simulating the operator. By varying the influx rate of the wastewater to the anaerobic filter the computer kept the system at an optimal organic load. The results obtained were equivalent to those obtained by permanent control of the system by an operator.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01950153
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  • 9
    Electronic Resource
    Electronic Resource
    Failure to reduce cholesterol as explanation for the limited efficacy of antihypertensive treatment in the reduction of CHD (1987)
    Springer
    Journal of molecular medicine 65 (1987), S. 828-832 
    Details
    ISSN: 1432-1440
    Keywords: Cholesterol ; Intervention ; Hypertension ; CHD reduction ; Trials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Over the past 6 years, major hypertension intervention studies in Europe, Australia, and the USA have shown disappointing results in the prevention of coronary heart disease (CHD) in spite of adequate treatment and good compliance. Recently, it has become increasingly clear that hypertensives with or without treatment display higher cholesterol levels than normotensive persons. The present review examines cholesterol levels in six intervention studies, none of which offered dietary or drug therapy for hypercholesterolemic patients. The Oslo study and the British MRC Trial reported very high average cholesterol levels and both showed no protection from CHD through intensive therapy in comparison to control patients. The Australian and the American MRFIT studies produced evidence for reduced coronary mortality among hypertensives with low in contrast to those with high cholesterol levels. The European Working Party showed indirectly that patients with marked reduction in blood pressureand cholesteral had a significantly lower cardiac mortality compared to placebo-treated patients. The IPPPSH study found that increasing cholesterol levels in hypertensives under beta blockeror diuretic therapy increased the risk of myocardial infarction. Failure to reduce cholesterol in hypertensive patients apparently is a major reason for the limited efficacy of antihypertensive treatment in the reduction of CHD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01727479
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  • 10
    Electronic Resource
    Electronic Resource
    Influence of dietary sodium restriction on lipid metabolism (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 990-992 
    Details
    ISSN: 1432-1440
    Keywords: Salt restriction ; Lipoproteins ; Cholesterol ; Obesity ; Hypertension
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The possible increase in total and low-density lipoprotein cholesterol following severe restriction of dietary NaCl was reported in 1990 and and 1991 from three experiments, one in the United States and two in Germany. Each of these experiments lasted only 1 week. To evaluate the clinical side effects we analyzed data collected from patients who completed a course of NaCl-restricted weight reduction at the Duke Diet and Fitness Center. Observations of lipid changes are not available for periods of less than 3 weeks; however, we were able to collect data on lipid and lipoprotein changes from 556 participants 25 days after they were referred for weight reduction. Total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels returned to normal in the majority of obese patients. In our slightly longer observation period in patients on a 1000 mg NaCl restricted diet we found no evidence of hyperlipidemic side effects. We believe that the hyperlipidemia resulting from severe sodium restriction in non-hypertensive, normal-weight individuals is not relevant to the problem of nonpharmacological and diuretic treatment of obese hypertensive patients. In clinically healthy, normal-weight, normotensive individuals severe salt restriction serves no practical or therapeutic purpose.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00180029
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