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  • Articles: DFG German National Licenses  (3)
  • Biopsy  (2)
  • Key words: MRI—Liver—Focal nodular hyperplasia—SPIO—Gd-DOTA—Gd-EOB-DTPA.  (1)
  • Key words: Thyroid  (1)
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  • Articles: DFG German National Licenses  (3)
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  • 1
    ISSN: 1432-0509
    Keywords: Key words: MRI—Liver—Focal nodular hyperplasia—SPIO—Gd-DOTA—Gd-EOB-DTPA.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Background: To demonstrate the improved specificity of liver MRI in diagnosis of focal nodular hyperplasia (FNH) using liver specific contrast agents. Methods: In a patient after resected adenosarcoma of the uterus a focal nodular hyperplasia was followed. Serial MRI of the liver was performed using first Gd-DOTA, followed by superparamagnetic iron oxide (SPIO) as well as Gd-EOB-DTPA. Results: During the follow-up of FNH specificity of liver MRI improved using liver specific contrast agents. The central scar as well as the pseudocapsule showed different typical contrast uptake using all three methods. Conclusion: Serial MRI of the liver with Gd-DOTA, SPIO and Gd-EOB-DTPA can exclude a malignant liver lesion. Liver biopsy of FNH can be avoided with increased specificity of MRI for FNH.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1084
    Keywords: Key words: Thyroid ; Biopsy ; Interventional MR ; MR guidance ; Stereotaxis ; Ultrasound
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The aim of this study was to demonstrate the clinical feasibility and utility of an interactive MR-guidance system to target and biopsy thyroid lesions, and to compare resolution between ultrasound and interventional MR imaging in the evaluation of thyroid lesions. Twenty thyroid lesions of 18 patients were interactively biopsied using a 0.5-T superconducting open magnet system. Stereotactic localization of the needle and imaging was accomplished using T1-weighted gradient-recalled-echo (GRE) images. Representative cytological material was retrieved in 16 of 20 lesions (benign cystic or colloid goiter: n = 14; one de Quervain's thyroiditis and one follicular neoplasia). Lesions smaller than 1.5 cm detected by ultrasound could not be visualized adequately on GRE images. Lesions smaller than 1.5 cm were successfully biopsied by ultrasound (three colloid and haemorrhagic goiters and one adenoma). Magnetic-resonance-guided interactive biopsies and positioning of non-ferromagnetic needles in the thyroid gland are technically feasible and safe. Compared with high-resolution ultrasound, lesions larger than 1.5 cm can be adequately visualized and biopsied. Magnetic-resonance-guided placement of non-ferromagnetic needles is no substitute for high-resolution ultrasound in clinical work-up of thyroid lesions.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Endometriose ; Biopsie ; Nadel ; Magnetresonanztomographie ; Interventionelle Radiologie ; Key words Endometriosis ; Biopsy ; needle ; Magnetic resonance imaging ; Interventional radiology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Introduction and Methods: A 0.5 T open-configuration MR system allows free access to the patient via a 58-cm-wide opening on both sides of the machine. A newly developed system for needle guidance enables the examiner to perform biopsies in combination with real-time imaging and to position laser fibers in the human body. For imaging, a 2D gradient echo sequence is used (TR 19 ms, TE 9 ms, flip angle 30 °, FOV 24 × 24 cm, slice thickness 10 mm matrix 256 × 128). The acquired images are displayed on two LCD screens localized within the MR system, thus allowing an interactive needle guidance. This procedure is illustrated by a case report. Discussion: The handling of the system for needle guidance was simple, mainly due to a real-time adaption of the scan plane to the needle direction. The possibility of multi-angulated approaches makes biopsies of hardly accessible anatomic regions feasible. Conclusion: We think that MR-guided needle positioning will play an important role in combination with thermosensitive therapies. Thermosensitivity of MR imaging allows extensive monitoring of such interventions.
    Notes: Zusammenfassung Ein offenes, interventionelles MR-Gerät (0,5 Tesla) erlaubt durch eine 58 cm breite Öffnung den Zugang zum im Gerät liegenden Patienten. Ein spezielles Punktionssystem ermöglicht es, unter Echtzeitbildgebung Punktionen vorzunehmen sowie auch Laserfasern im menschlichen Körper zu plazieren. Zur Bildgebung wird eine 2d-Gradientenechosequenz verwendet (TR 19 ms, TE 9 ms, Flipwinkel 30 °, FOV 24 × 24 cm, Schichtdicke 10 mm, Matrix 256 × 128). Die akquirierten Bilder werden dem punktierenden Radiologen auf 2 im Gerät angebrachten LCD-Monitoren angezeigt, wodurch eine interaktive Nadelführung ermöglicht wird. Es wurden bereits zahlreiche Punktionen an Patienten durchgeführt. Wichtig wird die MR-gesteuerte Punktion von Läsionen in Kombination mit der Durchführung thermosensitiver Therapien. Die der MR-Bildgebung inhärente Temperatursensitivität ermöglicht ein umfassendes Monitoring solcher Eingriffe in Echtzeit.
    Type of Medium: Electronic Resource
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