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  • Articles: DFG German National Licenses  (3)
  • Primary hyperparathyroidism  (2)
  • Bromoacetyl-3,3',5-tri[3'-^1^2^5I]iodo-L-thyronine, N-  (1)
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  • Articles: DFG German National Licenses  (3)
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  • 1
    ISSN: 0014-5793
    Keywords: (Rat heart mitochondria) ; Adenine nucleotide translocase ; Bromoacetyl-3,3',5-tri[3'-^1^2^5I]iodo-L-thyronine, N- ; Thyroid hormone
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1440
    Keywords: Primary hyperparathyroidism ; Histomorphometry ; Trabecular bone structure ; Parathyroid hormone ; Bone biopsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Iliac crest bone biopsy specimens of 391 patients with surgically proven primary hyperparathyroidism were investigated. In 60 unselected cases quantitative analysis of trabecular bone changes was performed. The age of the patients ranged between 12 and 85 years. The observed morphological findings were divided into four stages. In a few cases no differences from normal bone tissue could be observed. In 46% occurrence of a nonspecific increase of osteoid seams, osteoblasts, and osteoclasts was observed. Of the cases 50% showed a specific, but very often mild endosteal fibrosis. Only in 4% was there a severe fibroosteoclasia with development of so-called brown tumors. The quantitative analysis showed an increase of trabecular bone mass as well as of remodeling surfaces. But there was an overlap of up to 25% with the normal controls. The results demonstrate the influence of parathyroid hormone peptides on bone morphology. However, the investigation of a bone biopsy specimen is not generally very useful for diagnostic purposes.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 361 (1983), S. 593-597 
    ISSN: 1435-2451
    Keywords: Primary hyperparathyroidism ; Solitary adenoma ; Multiple gland disease ; Extrarenaler Hyperparathyreoidismus ; Solitäres Adenom ; Mehrdrüsenerkrankung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfasssung Bei 100 wegen extrarenalem Hyperparathyreoidismus operierten Patienten fand sich folgende Rezidiv-(Reoperations-)frequenz: solitäres Adenom 3 von 77 Patienten (3,8%), multiple Nebenschilddrüsenerkrankung 6 von 15 Patienten (42,3%) und Carcinom 3 von 8 Patienten (33,3%). Zum sicheren Erkennen einer Mehrdrüsenerkrankung bei der ersten Operation wird daher ein systematisches operatives Vorgehen empfohlen, wobei zunächst nur eine Halsseite exploriert wird; finden sich hierbei nicht ein Adenom und eine normale Nebenschilddrüse, ist die Revision der Gegenseite obligat. Hierdurch können die Folgen einer nicht notwendigen ausgedehnten Halsexploration oder Reoperation weitgehend vermieden werden.
    Notes: Summary In 100 patients operated on for primary hyperparathyroidism the following frequency of recurrent hyperparathyroidism (re-operation) was found: solitary adenoma 3 out of 77 patients (3.8%), multiple gland disease 6 out of 15 patients (42.3%), carcinoma 3 out of 8 patients (33.3%). To recognize a multiple gland disease at the first operation a systematic surgical approach is recommended starting with unilateral neck exploration; only if an adenoma and a normal parathyroid gland cannot be identified contralateral exploration is mandatory. Following this concept the risk of an unnecessary extended neck exploration or re-operation is avoided.
    Type of Medium: Electronic Resource
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