ISSN:
1615-6102
Keywords:
Rab7 protein
;
Endocytosis
;
Phagocytosis
;
Lysosomal enzymes
;
Cation-independent mannose 6-phosphate receptor
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary Small GTPases of the Rab subfamily localise to the cytoplasmic face of distinct membrane compartments and act as regulators of intracellular membrane traffic and transport vesicle formation. Among them, Rab7 controls the delivery of internalised material into degradative compartments and the acquisition of lysosomal hydrolases. This activity shapes the endocytic pathway of every cell type. In addition, this general role may adjust to serve specific needs in multicellular organisms.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01276850
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