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  • 1
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The effect of high-density lipoprotein (HDL) in protecting against atherosclerosis is usually attributed to its role in ‘reverse cholesterol transport’. In this process, HDL particles mediate the efflux and the transport of cholesterol from peripheral cells to the liver for further ...
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1438-1168
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Résumé Le massif de Guéret est situé dans la partie nord-orientale du Massif central français. I1 est formé principalement de granitoïdes, datés de 356 ± 10 Ma, qui définissent une association alumino-potassique. L'origine de cette association serait purement crustale pour certains auteurs alors que pour d' autres, la présence de roches mafiques en enclaves microgrenues et en stocks et filons fait envisager une éventuelle contribution mantellique. Les données de terrain ainsi que les données radiométriques disponibles s' accordent avec une intrusion quasiment simultanée des roches mafiques et des granitoïdes. Les caractéristiques texturales, minéralogiques et géochimiques de ces roches mafiques sont comparables à celles des vaugnérites à teneur faible en potassium ou à des redwitzites. Certaines textures de ces roches témoignent de la contamination d'un magma basique par une source crustale. Cependant, des processus tels que le mélange magmatique on l'assimilation par cristallisation fractionnée entre un pôle basique et les granitoïdes de Guéret ne s'accordent pas avec l'évolution géochimique de ces roches. Les corrélations positives existant entre le M index [100 * MgO/ (MgO + FeOt)] et SiO2, entre le K index [100 * K2O/(K2O + Na2O]) et SiO2, ainsi que entre certains éléments compatibles et incompatibles, sont plutôt en accord avec un processus de contamination par assimilation thérmique de I'encaissant. Dans ce type de processus, la contamination du magma basique serait par érosion thérmique de telle sorte que les magmas basiques les moins différenciés sont les plus contaminés. Or, l'évolution divergente des granitoïdes par rapport aux. vaugnérites ne permet pas d'évaluer la contribution des magmas basiques à la composition chimique des granitoïdes.
    Notes: Summary The Guéret massif (Massif Central, France) is mainly composed of granitoids that define an alumino-potassic association. An age of 356 ± 10 Ma is accepted for the intrusion of these granitoids for which a pure crustal origin has been suggested. However, the presence of mafic magmatic enclaves and of scattered stocks and dykes of amphibole-biotite mafic rocks also point to contribution of mantle-derived magmas in their genesis. From field relationships and radiometric data, the intrusion of the basic magmas is deduced to be quasi-simultaneous with the emplacement of granitoids. Petrologic, mineralogical and geochemical characteristics of the mafic rocks correspond to low-potassium vaugnerites or redwitzites. They are derived from a basic magma evolving by contamination with crustal components. However, pure magma mixing or assimilation by fractional crystallisation between mafic magmas and Guéret granitoids does not fit with the geochemical trends observed in both types of rocks. The positive correlation of M index [100 * MgO/(MgO +FeOt)] and K index [100 * K2O/(K2O + Na2O)] with respect to SiO2 in vaugnerites together with the positive correlation between compatible and incompatible trace-elements, rather favour the contamination of the basic magma by a wall rock assimilation process. However, dissimilar trends of vaugnerites and Guéret granitoids prevent to ascertain the role of basic magmas in granitoid genesis.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1615-6102
    Keywords: Rab7 protein ; Endocytosis ; Phagocytosis ; Lysosomal enzymes ; Cation-independent mannose 6-phosphate receptor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Small GTPases of the Rab subfamily localise to the cytoplasmic face of distinct membrane compartments and act as regulators of intracellular membrane traffic and transport vesicle formation. Among them, Rab7 controls the delivery of internalised material into degradative compartments and the acquisition of lysosomal hydrolases. This activity shapes the endocytic pathway of every cell type. In addition, this general role may adjust to serve specific needs in multicellular organisms.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 47 (1928), S. 75-79 
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 266 (1999), S. 175-180 
    ISSN: 1572-946X
    Keywords: galaxy ; mid-infrared ; active galactic nucleus ; starburst
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We present a new diagnostic diagram based on ISOCAMspectra (5-16 μm) to distinguish the emission inducedby the active galactic nucleus (AGN) from that associated with thestar formation activity. This diagnostic based on the mid-IRcontinuum and the Unidentified Infrared Band (UIB) intensity allowsus to estimate the relative importance of the three components (HIIregions, diffuse/photo-dissociation regions (PDRs), and AGN) contained ingalaxy mid-infrared emission. In AGN spectra, we confirm the absenceof UIBs presumably photodissociated by the X-UV radiation field. Inaddition, a non-negligible continuum below 9 μm commonlyassociated with emission from hot dust is present in AGNs. Adiagnostic diagram derived from these two results can be used fordetecting obscured AGNs embedded in a large concentration of dust.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 269-270 (1999), S. 349-355 
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We present some highlights from the mid-infrared (5–16 μm) images of mergers of massive galaxies obtained with the Infrared Space Observatory(ISO). We have observed: 1) ultraluminous infrared nuclei, 2) luminous dust-enshrouded extranuclear starbursts, and 3) active galaxy nuclei (AGNs). In this contribution we discuss the observations of Arp 299, a prototype for very luminous infrared galaxies, the Antennae which is a prototype of mergers, and Centaurus A which is the closest AGN to Earth. From these observations we conclude the following: 1) the most intense starbursts in colliding systems of galaxies and the most massive stars are dust-enshrouded in regions that appear inconspicuous at optical wavelengths, 2) the most intense nuclear infrared sources are a combination of AGN and starburst activity, 3)the hosts of radio loud AGNs that trigger giant double-lobe structures may be symbiotic galaxies composed of barred spirals inside ellipticals.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 266 (1999), S. 99-104 
    ISSN: 1572-946X
    Keywords: galaxy ; mid-infrared ; starburst
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract In this paper, we present ISOCAM mid-IR broad band images and spectraof three well known interacting galaxies. These are the prototypicalultraluminous IR galaxy Arp 220, and NGC 6240, which are classifiedas major mergers resulting from a collision of two disk galaxies ofapproximately equal mass, and the prime example of collisional ringgalaxies, the Cartwheel. Our observations provide a new powerful tooland shed some more light to the properties of the hot dust and starformation in interacting galaxies.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 269-270 (1999), S. 357-364 
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We present a set of spectral characteristics distinguishing optically selected active galactic nuclei (AGNs) from starbursts in the mid-IR. In AGN spectra, the Unidentified Infrared Bands (UIBs) are not detected which is probably due to the destruction of their carriers by the UV-X radiation field. In addition, a non-negligible continuum below 10 μm commonly associated with emission from very hot dust is exclusively present in AGNs. On the contrary, starburst spectra present clearly detected UIBs with a faint underlying continuum between 5–10 μm. Based on these features, we build a mid-IR diagnostic diagram to identify emission induced by the AGN and that associated with the star formation activity. This diagnostic based on the mid-IR continuum and the UIB intensity allows us to estimate the relative importance of the three components (HII regions, photo-dissociation regions (PDRs), and AGN) contained in the integrated mid-IR emission of galaxies. Our diagnostic diagram can be applied to reveal the presence of very obscured active nuclei behind large columns of dust.
    Type of Medium: Electronic Resource
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