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  • Articles: DFG German National Licenses  (2)
  • Chronic lymphocytic leukaemia  (1)
  • Erythroleukämie  (1)
  • Megakaryocyte  (1)
  • 1
    ISSN: 1432-0584
    Keywords: Non-Hodgkin lymphoma ; Chronic lymphocytic leukaemia ; Immunocytoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Clinical data of 116 patients with chronic lymphocytic leukaemia (CLL) and of 114 patients with lymphoplasmacytic/lymphoplasmacytoid lymphoma (synonym: LP immunocytoma, IC) as diagnosed according to the Kiel classification were compared. This interim evaluation of a prospective multicenter study of the Kiel Lymphoma Study Group characterizes IC the less favorable lymphoma entity as evidenced by a more rapid lymph node enlargement, by a higher incidence of constitutional symptoms and of marked anaemia, and by a higher percentage of patients requiring early treatment. In addition, in IC autoimmune haemolytic anaemia was detected in 11.2% of investigated patients as compared to none of the patients with CLL, and monoclonal gammopathy was disclosed in 34.2% of investigated patients as compared to only three patients with CLL who could be, however, unrecognized cases of IC. Actuarial survival data after a follow-up period of 40 months are in favor of an overall better prognosis of patients with CLL than of patients with IC.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 52 (1974), S. 649-650 
    ISSN: 1432-1440
    Keywords: Megakaryocyte ; chronic myelocytic leukemia ; acute leukemia ; erythroleukemia ; Megakaryocyt ; chronisch myeloische Leukämie ; akute Leukämie ; Erythroleukämie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In vereinzelten Fällen von chronisch myeloischer Leukämie, akuter Leukämie und Erythroleukämie wurden neben „Mikrokaryocyten“ noch kleinere Formen des megakaryocytären Systems unter 300µm2 im Knochenmark und teilweise im Blut gefunden. Mit Fortschreiten dieser Erkrankung nimmt die Anzahl dieser Zellen zu. Dem morphologischen Erscheinungsbild nach kann es sich um Degenerationsformen der „Mikrokaryocyten“ bzw. kleiner Megakaryocyten handeln.
    Notes: Summary Fifteen of 63 cases of chronic myelocytic leukemia, acute leukemia and erythroleukemia showed, in addition to microkaryocytes, another abnormal type of megakaryocytes which were smaller than 300µm2 and of different morphological appearance. These extremely small megakaryocytes appeared in 4 of 15 patients in the peripheral blood. The relative frequency of the cells increased with the progress of the disease. The morphologic appearance suggests that these cells are degenerative forms of microkaryocytes or of small megakaryocytes.
    Type of Medium: Electronic Resource
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