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  • Articles: DFG German National Licenses  (3)
  • HIV-1-Infektion  (2)
  • Histological classification  (1)
  • 1
    Electronic Resource
    Electronic Resource
    HIV-1-prävalenz bei drogentoten in verschiedenen großstädten der bundesrepublik Deutschland und in Westberlin zwischen 1985 und 1988 (1990)
    Springer
    International journal of legal medicine 103 (1990), S. 407-414 
    Details
    ISSN: 1437-1596
    Keywords: i.v.-drug addiction ; HIV-1-prevalence ; Drug deaths ; HIV-1infection ; HIV-1-prevalence ; regional differences ; i.v.-Drogenabhängige ; HIV-1-Prävalenz ; Drogentote ; HIV-1-Infektion ; HIV-1-Prävalenz ; regionale Unterschiede
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Ausgewertet wurde die HIV-Seroprävalenz bei Drogentoten in Westberlin, Frankfurt, München, Hamburg, Bremen, Köln und Stuttgart in den Jahren 1985–1988 (n = 753); im Jahre 1988 wurden 43% von insgesamt 674 Drogentoten erfaßt. Die Prävalenz lag regional zwischen 15 und 25%; nur in Berlin betrug sie 42%. Kumuliert belief sich die Prävalenz in allen Städten über den gesamten Untersuchungszeitraum auf 26%. Zu beobachten war ein Überwiegen des männlichen Geschlechts bei den getesteten Rauschgifttoten. Die kumulierte HIV-1-Prävalenz bei den Frauen (40%) war doppelt so hoch wie bei den Mdnnern (22%). Der Altersdurchschnitt sowohl der männlichen Rauschgifttoten als auch der mannlichen HIV-Positiven lag um 2–3 Jahre höher als bei den Frauen. Durch eine kontinuierliche Erfassung der HIV-1-Prävalenz bei den Rauschgifttoten kann die Rechtsmedizin einen Beitrag zur Erfassung des Ausbreitungsmodus in der Risikogruppe der i.v.-Drogenabhdngigen leisten.
    Notes: Summary The development of the HIV-1-prevalence among drug deaths (n = 753) in several German cities (Westberlin, Frankfurt, Munich, Hamburg, Bremen, Cologne and Stuttgart) from 1985 to 1988 was evaluated; in 1988 43% of 674 deceased drug addicts were examined. The regional prevalence rate was between 15 and 25%; only in Berlin 42% of the drug deaths were HIV-infected (cumulated data of all cities over the 4-year-period: 26%). There was no uniform or steady regional development of HIV-1-prevalence in the different cities. The ratio men/women among drug deaths was 3:1. The HIV-1-prevalence among males was 22%, among females 40%. HIV-infected individuals were 2–3 years older than seronegatives. Predictions concerning the trend of prevalence rates are not possible up to now. Continuous monitoring of the HIV-status of drug deaths seems to be a worthful method to evaluate the spread of this disease among the risk group of intravenous drug addicts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00204705
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    HIV-1-Prävalenz bei Drogentoten in verschiedenen Großstädten der Bundesrepublik Deutschland und in Westberlin zwischen 1985 und 1988 (1990)
    Springer
    International journal of legal medicine 103 (1990), S. 407-414 
    Details
    ISSN: 1437-1596
    Keywords: i.v.-drug addiction ; HIV-1-prevalence ; Drug deaths ; HIV-1-infection ; HIV-1-prevalence ; regional differences ; i.v.-Drogenabhängige ; HIV-1-Prävalenz ; Drogentote ; HIV-1-Infektion ; HIV-1-Prävalenz ; regionale Unterschiede
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Ausgewertet wurde die HIV-Seroprävalenz bei Drogentoten in Westberlin, Frankfurt, München, Hamburg, Bremen, Köln und Stuttgart in den Jahren 1985–1988 (n=753); im Jahre 1988 wurden 43% von insgesamt 674 Drogentoten erfaßt. Die Prävalenz lag regional zwischen 15 und 25%; nur in Berlin betrug sie 42%. Kumuliert belief sich die Prävalenz in allen Städten über den gesamten Untersuchungszeitraum auf 26%. Zu beobachten war ein Überwiegen des männlichen Geschlechts bei den getesteten Rauschgifttoten. Die kumulierte HIV-1-Prävalenz bei den Frauen (40%) war doppelt so hoch wie bei den Männern (22%). Der Altersdurchschnitt sowohl der männlichen Rauschgifttoten als auch der männlichen HIV-Positiven lag um 2–3 Jahre höher als bei den Frauen. Durch eine kontinuierliche Erfassung der HIV-1-Prävalenz bei den Rauschgifttoten kann die Rechtsmedizin einen Beitrag zur Erfassung des Ausbreitungsmodus in der Risikogruppe der i.v.-Drogenabhängigen leisten.
    Notes: Summary The development of the HIV-1-prevalence among drug deaths (n=753) in several German cities (Westberlin, Frankfurt, Munich, Hamburg, Bremen, Cologne and Stuttgart) from 1985 to 1988 was evaluated; in 1988 43% of 674 deceased drug addicts were examined. The regional prevalence rate was between 15 and 25%; only in Berlin 42% of the drug deaths were HIV-infected (cumulated data of all cities over the 4-year-period: 26%). There was no uniform or steady regional development of HIV-1-prevalence in the different cities. The ratio men/women among drug deaths was 3∶1. The HIV-1-prevalence among males was 22%, among females 40%. HIV-infected individuals were 2–3 years older than seronegatives. Predictions concerning the trend of prevalence rates are not possible up to now. Continuous monitoring of the HIV-status of drug deaths seems to be a worthful method to evaluate the spread of this disease among the risk group of intravenous drug addicts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01263149
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    The bcl-2/JH gene rearrangement is undetectable in Hodgkin's lymphomas: results from the German Hodgkin trial (1995)
    Springer
    Virchows Archiv 426 (1995), S. 37-41 
    Details
    ISSN: 1432-2307
    Keywords: Lymphoma ; Hodgkin's disease ; Polymerase chain reaction ; Immunohistochemistry ; Histological classification
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Ninety-one Hodgkin's lymphomas (HD), 52 non-Hodgkin lymphomas (NHL) and 33 specimens of non-neoplastic lymphatic tissues were investigated by polymerase chain reaction (PCR) for the presence of the bcl-2/JH gene rearrangement. The majority of the HD cases were drawn from the files of the German Hodgkin trial where diagnoses are established by a panel of four independent histopathologists. Using the very sensitive PCR method which detected 1 positive among 10000 negative cells, the bcl-2/JH gene rearrangement was found in 7/52 NHL and 3/16 tonsils with follicular hyperplasia, but in none of the 91 HD. The bcl-2 protein, however, was expressed by malignant cells of B and T cell lymphomas and by the giant tumour cells in 2/13 HD lymphocyte predominant, 11/28 HD nodular sclerosing I, 14/17 HD nodular sclerosing II, 10/27 HD mixed cellularity and 3/3 HD lymphocyte depleted. The bcl-2/JH rearrangement is thus independent of protein over-expression, the latter being found in all types of lymphomas. Our results do not confirm the findings of others who have detected the bcl-2/JH rearrangement in HD. These discrepancies may be explained by differences in choice of material, the gene rearrangement actually occuring in bystander cells but not in Reed-Sternberg or Hodgkin cells, or by contamination.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00194696
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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