ISSN:
1432-1041
Schlagwort(e):
Nilvadipine
;
Hypertension
;
elderly patient
;
circadian rhythm
;
ambulatory blood pressure monitoring (ABPM)
;
adverse effects
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
,
Medizin
Notizen:
Summary. A newly developed calcium antagonist, nilvadipine, was administered to 7 hypertensive patients aged 75.6 y. Nilvadipine 4 mg b.d. decreased the average 24-h blood pressure significantly from 169/89 mm Hg to 152/81 mm Hg after 7 to 14 days without any change in the pulse rate. The circadian patterns of blood pressure and pulse rate were not affected by nilvadipine. Although the present study was a preliminary one done over a short period in a small number of patients, the results suggest that nilvadipine exerts an antihypertensive effect without altering the circadian pattern or the variability of blood pressure in elderly hypertensive patients.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00315439
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