ISSN:
1432-0428
Keywords:
Growth hormone
;
diabetic microangiopathy
;
basement membrane thickening
;
experimental diabetes
;
glomerular basement membrane
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Injection of porcine growth hormone (200 μg) or saline 5 days a week for 16 to 20 weeks in streptozotocin-diabetic rats showed that compared to saline growth hormone produced a 2 1/2-fold larger increase in glomerular capillary basement membrane thickness (2p=0.027). The possible significance of this effect of an elevated level of growth hormone for diabetic microangiopathy is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02342875
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