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  • Electronic Resource  (5)
  • 25.70.Lm  (2)
  • chicken  (2)
  • Amitriptyline  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Cardiovascular effects of paroxetine (1990)
    Springer
    Psychopharmacology 102 (1990), S. 379-382 
    Details
    ISSN: 1432-2072
    Keywords: Paroxetine ; Amitriptyline ; Electrocardiogram ; Blood pressure ; Systolic time intervals ; Plasma drug concentration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a double-blind clinical study, electrocardiogram, blood pressure and systolic time intervals were measured in 40 depressive patients treated with either paroxetine (30 mg/day) or amitriptyline (150 mg/day) for 6 weeks. While amitriptyline significantly increased the heart rate, the QTc interval and the PEP/LVET ratio, paroxetine did not alter any of the cardiovascular parameters measured.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02244107
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    EOG and ERG modifications induced in the chicken eye after blockade of catecholamine and 5-hydroxytryptamine biosynthesis (1990)
    Springer
    Documenta ophthalmologica 76 (1990), S. 47-53 
    Details
    ISSN: 1573-2622
    Keywords: Biosynthesis inhibitors ; chicken ; dopamine ; electrooculogram ; lectroretinogram ; 5-hydroxytryptamine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The involvement of catecholaminergic and indoleaminergic systems in the modulation of the standing potential of the eye was tested in chickens by means of an indirect electrooculography method and direct current electroretinogram recordings. D,L α- monofluoromethyl dopa (MFMD), 50 and 100 nmol), a highly specific inactivator of aromatic L-amino acid decarboxylase, was injected intravitreally. This treatment is known to induce a selective and irreversible blockade of dopamine and 5-hydroxytryptamine biosynthesis. Five hours after drug injection an important increase in the standing potential appeared. The light peak was delayed by about 5 min but its amplitude was unchanged. The return of the standing potential to basal value during maintained illumination was delayed by 5–10 min. The time course of the dark trough was not modified. The intensity-voltage functions were also studied for the various electroretinogram components, 5 hr after MFMD. The voltage of the b-wave was reduced (by 65% with the highest intensity), while the other components were little affected. Substantial reduction in dopamine and 5-hydroxytryptamine concentrations were found in treated retinas. These data, together with previous results, suggest that the standing potential of the chicken eye may be modulated by a balance between catecholamine and indoleamine systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00140497
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Electrooculographic study in the chicken after treatment with neurotoxin 6-hydroxydopamine (1989)
    Springer
    Documenta ophthalmologica 72 (1989), S. 83-91 
    Details
    ISSN: 1573-2622
    Keywords: chicken ; dark trough ; dopamine ; electrooculogram ; 6-hydroxydopamine ; light peak
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The implication of dopamine in the modulation of the standing potential of the eye was tested in the chicken by an indirect electrooculogram (EOG) method. After a single rapid systemic injection of dopamine, a transient dose-dependent increase in the EOG voltage was observed. EOG recordings during light and dark adaptation were performed after retinal dopamine depletion was induced by intraocular injections of the neurotoxin 6-hydroxydopamine (6-OHDA). The eyes were injected on two successive days with a mixture of 6-OHDA (50 μg), pargyline (a monoamine oxidase inhibitor), and ascorbate added as an antioxidant. Following this treatment EOG recordings were performed 1, 4, and 8 days after the second injection. The electrophysiological changes appeared most spectacular on the fourth day: an important increase in the EOG basal values as well as of the amplitude of the light peak and of the dark trough were observed. Substantial reduction in retinal concentration of dopamine was found in treated retinas. These unexpected electrophysiological data offer additional evidence for the involvement of a catecholamine in the generation of the light peak and the dark trough of the EOG.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00155217
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Results on two-, three-, and four-body events from the100Mo+100Mo and120Sn+120Sn collisions aroundE/A=20 MeV (1991)
    Springer
    The European physical journal 341 (1991), S. 53-73 
    Details
    ISSN: 1434-601X
    Keywords: 25.70.-z ; 25.70.Lm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Events with 2, 3 and 4 heavy-fragments (A≧20) have been detected in the reactions100Mo+100Mo atE/A =18.7, 23.7 MeV and120Sn+120Sn atE/A=18.4 MeV. The experiments were performed with an array of 12 detectors which together covered a large fraction of the forward hemisphere and allowed a high detection efficiency for these events. Masses and energies of all fragments have been reconstructed by means of an improved version of the kinematic coincidence method. The probabilitiesP 3 andP 4 of producing 3- and 4-body events were found to depend mainly on the dissipated energy rather than on the bombarding energy, thus indicating that their origin lies more in the decay properties of the excited fragments than in the dynamics of the interaction. Emission of light particles from the composite system is shown to become more relevant with increasing bombarding energy and may explain the drop of theP 3 andP 4 curves at high energy losses. Small deviations of theP 3 andP 4 curves at 23.7A · MeV from those at lower bombarding energies were used to estimate the amount of a possible pre-equilibrium light particle emission as a function of impact parameter.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01281274
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  • 5
    Electronic Resource
    Electronic Resource
    Analysis of the sequential fission observed in collisions of100Mo +100Mo and120Sn +120Sn around 20 A·MeV (1995)
    Springer
    The European physical journal 351 (1995), S. 167-186 
    Details
    ISSN: 1434-601X
    Keywords: 25.70.Lm ; 25.85.−w
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Events with 2, 3 and 4 heavy fragments (A≥20) detected in the reactions100Mo +100Mo at 18.7, 23.7 A·MeV and120Sn +120Sn at 18.4 A·MeV were analyzed by means of an improved version of the kinematic coincidence method. The phase-space distributions prove that 3- (and possibly 4-) body events predominantly originate from a two-step mechanism and are compatible with the hypothesis of a binary deep-inelastic interaction followed by the further fissionlike decay of one (or both) of the primary fragments. The characteristics of the fission step — mass asymmetry, relative velocity, in-plane and out-of-plane angles — have been reconstructed for the 3-body events and indications are found that nonequilibrium effects at the end of the deep-inelastic phase may influence the fissionlike decay.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01289527
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    Paper (German National Licenses)
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