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  • Electronic Resource  (3)
  • Antioxidant enzymes  (1)
  • Blood pH  (1)
  • Exercise  (1)
  • 1
    ISSN: 1439-6327
    Keywords: Electrolytes ; Fluid balance ; Glucose ; Exercise metabolism ; Blood pH
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The purpose of these experiments was to examine the influence of various fluid replacement drinks on exercise-induced disturbances in homeostasis during heavy exercise. Nine trained cyclists performed constant load exercise on a cycle ergometer to fatigue on three occasions with 1-week separating experiments. The work rate was set initially at ∼ 85% of $$\dot V_{o_{2{\text{ }}max} } $$ (range 82–88%) with fatigue being defined as a 10% decline in power output below the initial value. During each experiment subjects consumed one of the following three beverages prior to and every 15 min during exercise: (1) non-electrolyte placebo (NEP; 31 mosmol · kg−1); (2) glucose polymer drink containing electrolytes (GP; 7% CHO, 231 mosmol · kg−1), and (3) electrolyte placebo drink without carbohydrate (EP; 48 mosmol · kg−1). Both the GP and EP beverage contained sodium citrate/citric acid (C) as a flavoring agent while C was not contained in the NEP drink. Although seven of nine subjects worked longer during the GP and EP treatment when compared with the NEP trial, the difference was not significant (P〉0.05). No differences (P〉0.05) existed between the GP and EP treatments in performance time. Exercise changes in rectal temperature, heart rate, Δ % plasma volume and plasma concentrations of total protein, free fatty acids, glucose, lactate, potassium, chloride, calcium, and sodium did not differ (P〉0.05) between trials. In contrast, blood hydrogen ion concentration [H+] was significantly lower (P〈0.05) at 30 min of exercise during the GP and EP treatment when compared with the NEP run. These data provide evidence that electrolyte drinks do not minimize exercise-induced disturbances in blood-electrolyte concentrations during heavy execrcise when compared with nonelectrolyte drinks; however, these results suggest that fluid replacement beverages containing buffers (i.e. C) and/or electrolytes may minimize blood alterations in [H+] during intense exercise. Additional research is required to determine if the buffering influence of these beverages has an ergogenic benefit during heavy exercise.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1439-6327
    Keywords: Exercise ; Induced hypoxemia ; Incremental exercise ; Trained athletes ; Arterial oxyhemoglobin saturation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Recent evidence suggests that exercise-induced hypoxemia (EIH) may occur in healthy trained endurance athletes. However, at present, no data exist to describe the regularity of EIH in athletes or non-athletes. Therefore, the purpose of the present investigation was to determine the incidence of EIH during exercise in healthy subjects varying in physical fitness. Subjects (N=68) performed an incremental cycle ergometer test to volitional fatigue with percent arterial oxyhemoglobin saturation (%SaO2) measured min-by-min. For the purpose of data analysis subjects were divided into three groups according to their level of physical training: 1) untrained (N=16), 2) moderately trained (N=27), and 3) elite highly trained endurance athletes (N=25). EIH was defined as a %SaO2 of ≤91% during exercise. EIH did not occur in any of the untrained subjects or the moderately trained subjects. However, EIH occurred in 52% of the highly trained endurance athletes tested and was highly reproducible (r=0.95; P〈0.05). These findings further confirm the existence of EIH in healthy highly trained endurance athletes and suggests a rather high incidence of EIH in this healthy population. Hence, it is important that the clinician or physiologist performing exercise testing in elite endurance athletes recognize that EIH can and does occur in the elite endurance athlete in the absence of lung disease.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1439-6327
    Keywords: Key words Fatigue ; Antioxidant enzymes ; Non-protein thiols ; Lipid peroxidation ; Oxidative stress
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Endurance exercise training promotes a small but significant increase in antioxidant enzyme activity in the costal diaphragm (DIA) of rodents. It is unclear if these training-induced improvements in muscle antioxidant capacity are large enough to reduce oxidative stress during prolonged contractile activity. To test the hypothesis that training-related increases in DIA antioxidant capacity reduces contraction-induced lipid peroxidation, we exercise trained adult female Sprague-Dawley (n = 7) rats on a motor-driven treadmill for 12 weeks at ≈ 75% maximal O2 consumption (90 min/day). Control animals (n = 8) remained sedentary during the same 12-week period. After training, DIA strips from animals in both experimental groups were excised and subjected to an in vitro fatigue contractile protocol in which the muscle was stimulated for 60 min at a frequency of 30 Hz, every 2 s, with a train duration of 330 m. Compared to the controls, endurance training resulted in an increase (P 〈 0.05) in diaphragmatic non-protein thiols and in the activity of the antioxidant enzyme superoxide dismutase. Following the contractile protocol, lipid peroxidation was significantly lower (P 〈 0.05) in the trained DIA compared to the controls. These data support the hypothesis that endurance exercise training-induced increases in DIA antioxidant capacity protect the muscle against contractile-related oxidative stress.
    Type of Medium: Electronic Resource
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