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  • Electronic Resource  (22)
  • Inorganic Chemistry  (12)
  • cGMP-dependent protein kinase  (5)
  • Myosin light chain kinase  (3)
  • Polymer and Materials Science  (2)
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  • Electronic Resource  (22)
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Keywords
  • 1
    Electronic Resource
    Electronic Resource
    The calmodulin fraction responsible for contraction in an intestinal smooth muscle
    Amsterdam : Elsevier
    FEBS Letters 170 (1984), S. 383-386 
    Details
    ISSN: 0014-5793
    Keywords: Calmodulin ; Contraction control ; Myosin light chain kinase ; Smooth muscle ; Taenia coli
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(84)81349-6
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  • 2
    Electronic Resource
    Electronic Resource
    The influence of P-light chain phosphorylation by myosin light chain kinase on the calcium sensitivity of chemically skinned heart fibres
    Amsterdam : Elsevier
    FEBS Letters 189 (1985), S. 221-224 
    Details
    ISSN: 0014-5793
    Keywords: Chemically skinned heart fibre ; Myosin light chain kinase ; P-light chain ; Phosphorylation
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(85)81027-9
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  • 3
    Electronic Resource
    Electronic Resource
    High-level expression of functional cGMP-dependent protein kinase using the baculovirus system
    Amsterdam : Elsevier
    FEBS Letters 336 (1993), S. 163-167 
    Details
    ISSN: 0014-5793
    Keywords: Baculovirus expression ; cGMP-dependent protein kinase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(93)81632-A
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  • 4
    Electronic Resource
    Electronic Resource
    cGMP-dependent protein kinase decreases calcium sensitivity of skinned cardiac fibers
    Amsterdam : Elsevier
    FEBS Letters 149 (1982), S. 171-175 
    Details
    ISSN: 0014-5793
    Keywords: Skinned cardiac muscle ; Troponin-I phosphorylation ; cGMP-dependent protein kinase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(82)81095-8
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  • 5
    Electronic Resource
    Electronic Resource
    Autophosphorylation of cGMP-dependent protein kinase is stimulated only by occupancy of one the two cGMP binding sites
    Amsterdam : Elsevier
    FEBS Letters 164 (1983), S. 350-354 
    Details
    ISSN: 0014-5793
    Keywords: 8-Benzyl-amino-cAMP ; Autophosphorylation ; N^2-Monobutyryl-c-GMP ; cGMP-dependent protein kinase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(83)80315-9
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  • 6
    Electronic Resource
    Electronic Resource
    Cyclic AMP-dependent protein kinase does not phosphorylate cyclic GMP-dependent protein kinase in vitro
    Amsterdam : Elsevier
    FEBS Letters 151 (1983), S. 71-75 
    Details
    ISSN: 0014-5793
    Keywords: Autophosphorylation ; Heat-stable inhibitor protein ; cAMP-dependent protein kinase ; cGMP-dependent protein kinase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(83)80345-7
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  • 7
    Electronic Resource
    Electronic Resource
    Cyclic GMP-dependent protein kinase relaxes skinned fibers from guinea pig taemia coli but not from chicken gizzard (1986)
    Springer
    Pflügers Archiv 407 (1986), S. 87-91 
    Details
    ISSN: 1432-2013
    Keywords: cGMP ; cGMP-dependent protein kinase ; Cyclie nucleotides in skinned smooth muscle ; Skinned guinea pig taenia coli ; Skinned chicken gizzard
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of cGMP and cGMP-dependent protein kinase (cG-PK) on contraction and relaxation was studied in skinned smooth muscle fibers from guinea pig taenia coli and chicken gizzard. At a fixed [Ca2+] relaxation was significantly enhanced by activated cG-PK in fibers from guinea pig taenia coli, but not in those from chicken gizzard. The Ca2+-requirement for half maximal tension maintenance was shifted to the right. Relaxation was associated with a decline in phosphorylated myosin light chain-2 from 34% to 25%. Similarly to relaxation activated cG-PK inhibited tension development only in fibers from taenia coli. These results suggest that mammalian and chicken smooth muscle fibers respond differently to cG-PK.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00580726
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of calcium-antagonist and calmodulin-antagonist drugs on calmodulin-dependent contractions of chemically skinned vascular smooth muscle from rabbit renal arteries (1983)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 323 (1983), S. 85-89 
    Details
    ISSN: 1432-1912
    Keywords: Myosin light chain kinase ; Vasodilator drugs ; Fendiline ; Nifedipine ; Verapamil
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. Renal arteries from rabbits were chemically skinned by incubation with Triton X-100, and subsequently stored in buffered glycerol. 2. In the presence of Mg-ATP, of EGTA-buffered calcium, and of calmodulin, miniature strips of the skinned arteries developed tension the strength of which was approx. 15–20% of that of viable renal arteries. 3. Tension development was dependent on the concentration of both calcium and calmodulin. 4. The effect of eight vasodilator drugs, the majority of them being “calmodulin antagonists” or “calcium antagonists”, on the skinned arteries was assessed. In concentrations up to 10−3 M, verapamil, D-600, and hydralazine proved to be ineffective, and the same was found with the dihydropyridine derivatives, nifedipine and felodipine, at 0.6×10−3 M and 0.8×10−4 M, respectively, i.e. at saturation in a 9∶1 contracting buffer/ethanol mixture (v/v). 5. In a concentration-dependent manner, trifluoperazine, W-7, and fendiline relaxed Ca-calmodulin-induced tension or prevented tension development when given prior to the activation by Ca-calmodulin. However, considerably higher concentrations of the drugs were necessary for half-maximal relaxation than the reported concentrations for half-maximal saturation of hydrophobic binding sites at the calmodulin molecule. 6. These findings suggest that at therapeutic blood levels, the vasodilator properties of calcium antagonists and other direct vasodilators cannot be explained by interference with the binding of myosin light chain kinase to calmodulin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00634253
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  • 9
    Electronic Resource
    Electronic Resource
    Untersuchung der Verbindungseigenschaften an laserstrahlgefügten Brillengestellen (1998)
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 29 (1998), S. 281-291 
    Details
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Investigation of Laser Beam Joining Properties for Eye Glass Frame ManufactureIn the production of high-grade eye glass frames of stainless steel increase the application of laserbeam joining technology in comparison to conventional processes. In a study it should be established, with which process (brazing or welding), the practical requirements of eye glass frames could be realized. Profiles made of Cr-Ni-steel which are used in practice due to their corrosion resistance, were joined with laser beam. To characterize the properties of joints, the quality of specimens were tested concerning mechanical properties (hardness, strength, ductility) and structural constitution. In relation to the requirement of good ductility of the joints, it was possible to proof the advantages of the welded samples.
    Notes: Bei der Fertigung von hochwertigen Brillengestellen aus nichtrostenden Stählen gewinnt der Einsatz der Laserstrahlfügeverfahren im Vergleich zu konventionellen Verfahren zunehmend an Bedeutung. Im Rahmen einer Studie sollte festgestellt werden, welches der beiden Verfahren Löten und Schweißen die in der Praxis gestellten Anforderungen an Brillengestelle besser erfüllt. Hierzu wurden Profile aus Cr-Ni-Stahl, wie sie in der Praxis wegen ihrer besonderen Langzeitstabilität gegenüber Korrosion eingesetzt werden, mittels Laserstrahl gefügt. Zur Charakterisierung der metallurgischen Eigenschaften der Fügeverbindungen wurden die Qualitätsmerkmale der Proben hinsichtlich mechanischer Eigenschaften (Härte, Festigkeit und Verformbarkeit) sowie die Gefügeausbildung untersucht. Im Hinblick auf die geforderte gute Verformbarkeit der Verbindungen konnte für die geschweißten Proben ein Vorteil gegenüber dem Laserstrahllöten nachgewiesen werden.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mawe.19980290607
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  • 10
    Electronic Resource
    Electronic Resource
    Hydroxidgruppen an Zeolithen. II. Zahl und Eigenschaften von Hydroxidgruppen an CeNaY- und HNaY-Zeolithen unterschiedlichen Austauschgrades (1974)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 404 (1974), S. 142-160 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Hydroxide Groups on Zeolites. II. Number and Properties of Hydroxide Groups on CeNaY and HNaY Zeolites of Different Exchange DegreeThe number of hydroxide groups on CeNaY and HNaY zeolites was examined by D2 exchange, and their properties in dependence of the cation exchange degrees were studied by IR spectroscopy. On CeNaY zeolites there exist six kinds and on HNaY zeolites at least seven kinds of hydroxide groups.On the CeNaY zeolites, the hydroxide groups are produced by dissociative chemisorption of water on Ce3+ ions. Their total number increases continuously with increasing exchange degree. Some of the hydroxide groups are acid BRÖNSTED centers whose number increases with increasing exchange degree and decreases with the temperature of preheating increasing to about 600°C.On the HNaY zeolites, the hydroxide groups are produced by thermal decomposition of the NH+4 ions, by dealumination and interaction of the Al3+ ions produced in this way in the place of cations with water. Above the threshold value of 35% the total number of the hydroxide groups increases very rapidly with increasing exchange degree. One part of the hydroxide groups decreasing with increasing exchange degree acts as acid BRÖNSTED centers. The number of these centers does not decrease until at preheating temperatures above 450°C.
    Notes: An CeNaY- und HNaY-Zeolithen wurden durch D2-Austausch die Zahl und infrarotspektroskopisch die Eigenschaften der Hydroxidgruppen in Abhängigkeit vom Kationenaustauschgrad untersucht. Es existieren an CeNaY-sechs Arten und an HNaY-Zeolithen mindestens sieben Arten von Hydroxidgruppen.An den CeNaY-Zeolithen entstehen die Hydroxidgruppen durch dissoziative Chemisorption von Wasser an Ce3+-Ionen. Ihre Gesamtzahl wächst kontinuierlich mit steigendem Austauschgrad. Einige der Hydroxidgruppen sind saure BRÖNSTED-Zentren, deren Zahl mit steigendem Austauschgrad wächst und mit steigender Vorerhitzungstemperatur bis etwa 600°C sinkt.An den HNaY-Zeolithen entstehen die Hydroxidgruppen durch thermische Zersetzung der eingetauschten NH+4-Ionen und mit wachsendem Austauschgrad zunehmend durch das Herauslösen von Gitteraluminium und Wechselwirkung der so entstehenden Al3+-Ionen auf Kationenplätzen mit Wasser. Die Gesamtzahl der Hydroxidgruppen wächst oberhalb des Schwellenwertes von 35% sehr stark mit steigendem Austauschgrad an. Ein mit steigendem Austauschgrad abnehmender Anteil der Hydroxidgruppen wirkt als saure BRÖNSTED-Zentren, deren Zahl erst bei Vorerhitzungstemperaturen oberhalb von 450°C abnimmt.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19744040206
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