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  • 1975-1979  (31)
  • 1930-1934  (3)
  • 1920-1924
  • 1979  (23)
  • 1977  (8)
  • 1930  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 3 (1977), S. 0 
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 33 (1977), S. 743-745 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Healthy rats and guinea-pigs were treated with a simple method of continuous peritoneal dialysis for 12, 24 and 48 h. Increasing with time, both animal species developed severe hypoproteinemia and hemoconcentration due to protein loss into the dialyzate fluid. These changes were associated with a high mortality rate, when Sterofundin® was used for dialysis. Therefore, protein loss should be substituted and the type of dialyzate must be considered in experimental long-term dialysis using these small laboratory animals.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 38 (1979), S. 435-446 
    ISSN: 1432-0584
    Keywords: Circulating immune complexes ; Malignant lymphoma ; Zirkulierende Immunkomplexe ; maligne Lymphome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mit der125J-Clq-Deviationsmethode nach Sobel, dem Polyethylenglykol-Präzipitationstests nach Nydegger und einer Sepharose 6B-Säulenchromatographie in Anlehnung an MacLennan wurden zirkulierende Immunkomplexe (ZIK) bei 20–27% der Patienten mit Hodgkin-Lymphomen, bei 8% der Patienten mit Nicht-Hodgkin-Lymphomen vom niedrigen und in 20–40% vom hohen Malignitätsgrad nachgewiesen. ZIK traten in fortgeschrittenen Stadien der Erkrankungen auf und korrelierten gut mit der Krankheitsaktivität. ZIK verschwanden in der Remission und erschienen im Rezidiv wieder. ZIK wurden nur bei Patienten mit allgemeinen Symptomen, d. h. mit B-Symptomen, gefunden. Die pathogenetische Rolle der ZIK bei der Entstehung der B-Symptome und bei der Tumorausbreitung ist noch nicht end gültig geklärt. Der Antikörperanteil der ZIK ist IgG, die antigene Komponente wurde nicht charakterisiert.
    Notes: Summary Using the125J-Clq deviation method according to Sobel, the polyethylenglycol precipitation test of Nydegger, and a Sepharose 6B column chromatography in a modification of MacLennan's method, circulating immune complexes (CIC) have been detected in 20–27% of patients with Hodgkin's lymphoma, in 8% of patients with non-Hodgkin lymphoma of low, and in 20–40% with high malignancy. CIC appeared in advanced stages of the diseases and correlated well with the activity of the disease. CIC disappeared in remissions and reappeared during reactivation of the disease. CIC were only found in patients with general symptoms, i.e. B-symptoms. The pathogenetic role of CIC in the initiation of B-symptoms and in tumor spread is still not fully explained. The antibody part of the CIC is IgG, the antigenic component has not yet been characterized.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 228 (1979), S. 311-325 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 224 (1977), S. 141-143 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
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    Unknown
    Roma : Periodicals Archive Online (PAO)
    Archivum historicum Societatis Iesu. 46 (1977) 225 
    ISSN: 0037-8887
    Topics: Theology and Religious Studies
    Notes: OPERUM, QUAE IUDICANTUR, INDEX
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  • 7
    ISSN: 1432-0584
    Keywords: Lymphocyte inhibitor ; Inhibition of proliferation ; Lymphocyte chalone ; Lymphozyten-Inhibitor ; Proliferationshemmung ; Lymphozyten-Chalon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Ein früher beschriebener, teilweise gereinigter Kalbsmilzextrakt weist bezüglich seiner biologischen Wirkung die Eigenschaften eines Lymphozytenchalons auf: er ist gewebsspezifisch, artunspezifisch, nicht toxisch und inhibiert die Zellproliferation reversibel. Dieser Extrakt wurde durch Ionenaustauschchromatographie mit DEAE-Sephacel aufgetrennt und liegt nun in 10 000-facher Anreicherung vor. Die aktivste Fraktion hemmte den Thymidineinbau von Phytohämagglutinin- oder Pokeweed-Mitogen-stimulierten Lymphozyten um 86% bzw. 70% in einer Konzentration von 100 ng/ml. Ehrlich-Ascites-Zellen wurden in derselben Konzentration nicht gehemmt. Der Hemmstoff wird mit anderen nicht bekanntgewordenen Lymphozyteninhibitoren verglichen.
    Notes: Summary A partially purified calf spleen extract, which exhibits the properties of a lymphocyte chalone (tissue-specific, species non-specific, non-toxic and reversible acting, endogenous inhibitor of cell proliferation) as concerning biological activities, has been described earlier. This fraction has been further purified by ion exchange chromatography with DEAE-Sephacel to a 10000-fold purification. The most active fraction inhibited3H-thymidine incorporation into phytohemagglutinin- or pokeweed-mitogen-stimulated lymphocytes by 86% resp. 70%, when given in a concentration of 100 ng/ml. Ehrlichascites-cells were not inhibited by the same concentration. The inhibiting activity is compared to other published lymphocyte inhibitors.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Planta 144 (1979), S. 391-400 
    ISSN: 1432-2048
    Keywords: Citrus ; Cuticular transpiration ; Cuticles ; Permeability (water) ; Vapor saturation deficit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Using the system vapor/membrane/liquid, permeability coefficients of cuticular transpiration (P ct) were determined as functions of water activity in the vapor (a wv). Enzymatically isolated cuticular membranes (CM) of Citrus aurantium L. and nonisolated CM of onion bulb scales and eggplant fruits were investigated. P ct of Citrus and eggplant CM decreased with decreasing a wv, while permeability coefficients of CM of onion were independent of a wv. Extraction of soluble cuticular lipids (SCL) from the CM of Citrus increased permeability coefficients by a factor of approximately 500. This extraction had no effect on the dependence of P ct on a wv. Treating cuticular membranes as a resistance network consisting of SCL and the polymer matrix, it is shown that the permeability of onion CM is determined by the resistance of the SCL arranged in series with the polymer matrix. In this type of CM liquid and vapor are separated by a continuous, nonporous layer of SCL, and the driving force of transpiration is the gradient of partial pressure of water vapor across the SCL layer. In the CM of Citrus and eggplant, the SCL layer is traversed by polar pores that swell or shrink depending on a wv. However, liquid continuity is maintained across these membranes down to a wv=0.22, the lowest value used. In this type of membrane the driving force of transpiration is the water potential gradient across the membrane.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-2013
    Keywords: Slow muscle fibres ; Action potential ; Nerve stump ; Temperature
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A. Pyriformis and extensor longus digiti IV muscles of Rana temporaria were denervated by cutting the sciatic or peroneal nerve at various distances from the muscles. Slow fibres were identified by their membrane time constants, and examined for their ability to produce action potentials in response to intracellularly applied current pulses. B. The slow muscle fibres acquired the ability to generate action potentials several days after denervation. The duration of this latent period depended on the length of the peripheral nerve stump, and on the temperature at which the frogs were kept after the operation. C. At 18°C the latent period increased by 0.36 days per mm of sciatic nerve stump. At 11.5° C the corresponding value was 0.7 days/mm. The effect of length of the peroneal nerve was smaller than that of the sciatic nerve. D. It is suggested that the peripheral nerve stump serves as a reservoir of ‘trophic’ material which is transported towards the slow fibres at a rate of 2.8 mm/day (at 18° C) and seems to block the formation of Na channels. TheQ 10 value of this transport system would be 2.7.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 382 (1979), S. 43-50 
    ISSN: 1432-2013
    Keywords: Slow fibres ; Contractile responses ; Effect of denervation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract 1. The contractile responses of single slow muscle fibres were investigated under isometric conditions. The fibres were isolated from normal and denervated iliofibularis muscles ofRana temporaria. Direct stimulation was achieved by external application of electrical pulses or depolarizing solutions (40 mM K and acetylcholine 10\t-6 g/ml). 2. Upon electrical stimulation normal slow fibres developed contractions whose amplitude increased steadily with the strength of the pulses. These contractions did not exceed 0.22 kg/cm2, and their rates of rise and fall were approximately 1/6 of those observed in twitch fibres. During pulses of several 100 ms duration the tension continued to rise slowly until the end of the pulses. Application of 40 mM K or acetylcholine resulted in contractures which reached maximum values of 1.71 and 1.87 kg/cm2, respectively, after less than 1 min; little relaxation occurred during the following minutes. 3. The responses of slow fibres denervated for 9−76 days differed in several respects from those of normal slow fibres. a) The contractions elicited by electrical stimulation became faster but their amplitude decreased; the relationship between tension and pulse strength remained, however, essentially unchanged. b) Small and short contractions could be observed during and at the end of stimulating current pulses. Their amplitude was independent of the amplitude and duration of the stimuli; they were blocked by tetrodotoxin and must be attributed to action potentials. c) The ability to develop and maintain tension was reduced. Maximum values of K- and acetylcholine contractures were generally only 50% of those observed in normal slow fibres. Maintenance of tension was markedly reduced in some fibres, less so in others. 4. It is concluded that incorporation of Na channels into its membrane does not transform the slow fibre into a type of fibre which resembles a twitch fibre.
    Type of Medium: Electronic Resource
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