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  • 2005-2009
  • 1980-1984  (5)
  • 1975-1979
  • 1983  (5)
  • 1
    Electronic Resource
    Electronic Resource
    IMMUNOHISTOCHEMICAL STUDY OF α-FETOPROTEIN IN RAT EMBRYOS DURING ONTOGENESIS (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 417 (1983), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1983.tb32866.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Polyglucosan bodies in the digestive tract of the aged dog (1983)
    Springer
    Acta neuropathologica 60 (1983), S. 297-300 
    Details
    ISSN: 1432-0533
    Keywords: Polyglucosan bodies ; Lafora-like bodies ; Aging ; Smooth muscles ; Digestive tract ; Dog
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In our recent studies on aging phenomena in animals, polyglucosan bodies (PGB) were found within the smooth muscle in the digestive tract of aged dogs without neurologic signs. PGB were basophilic, round, or oval bodies which appeared to have a homogenous or concentric shape. Their histochemical properties were characterized by the presence of glucose polymers (polyglucosan). Electron microscopy revealed that PGB were composed mainly of irregularly clustered, short branching filaments measuring about 90 Å in width. PGB were histochemically and ultrastructurally identical to the previously reported Lafora-like bodies in the CNS of aged dogs. PGB were found in all aged dogs and were disseminated throughout the digestive tract, especially in the cecum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691880
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Quantitative determination of urinary protein components of children with postural proteinuria (1983)
    Springer
    European journal of pediatrics 140 (1983), S. 268-272 
    Details
    ISSN: 1432-1076
    Keywords: Postural proteinuria ; Urinary protein components ; Upright lordotic posture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Twenty-one protein components were measured in urine specimens from 12 subjects with postural proteinuria in the recumbent posture and after a period of upright lordotic posture. The lordotic posture produced an increased urinary excretion of total protein and 19 protein components, particularly of albumin, IgG globulin, and transferrin (128, 68, and 167-fold, respectively). However, 90 min after the lordotic posture, most of the protein components returned to initial values, whereas albumin, IgG globulin, and transferrin remained high. β2-Microglobulin, retinol binding protein, and lysozyme showed the smallest increases after the lordotic posture. These findings suggest that proteinuria occurring after the lordotic posture may be characterized by an increased glomerular permeability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00443374
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Organic acids and branched-chain amino acids in body fluids before and after multiple exchange transfusions in maple syrup urine disease (1983)
    Springer
    Journal of inherited metabolic disease 6 (1983), S. 183-189 
    Details
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We successfully treated a critically ill infant with the classical type of maple syrup urine disease by multiple exchange tranfusions via a peripheral artery and vein and with positive supplementation in the early stage of therapy. Clinical improvement was definite after the plasma leucine level fell below 1 mmol/l. There was a close linear correlation between plasma concentrations of branched-chain amino acids and their corresponding branched-chain α-keto acids and branched-chain α-hydroxy acids. α-Hydroxy acids were more easily excreted in the urine than α-keto acids and amino acids. Our studies on urinary organic acids supported the existence of minor metabolic pathways of branched-chain α-keto acids, although they were not though to be important in eliminating accumulated α-keto acids. Urinary excretion of succinic acid and α-ketoglutaric acid, which are components of the citric acid cycle, increased transiently during the patient's convalescence. The cerebrospinal fluid/plasma ratios for branched-chain amino acids, α-keto acids, and α-hydroxy acids were very high before the transfurions and decreased after improvement. The cerebrospinal fluid/plasma rations for 5-carvon acids, α-ketoisovaleric acid and α-hydroxyisiovaleric acid were much higher than for other branched-chain acids not only in the patients but also in normal controls. Cerebrospinal fluid levels of α-ketoisocaproic acid and α-hydroxyisovaleric acid were as high as 1 mmol/l in our patient.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02310879
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Skeletal muscle tension, flow, pressure, and EMG during sustained isometric contractions in humans (1983)
    Springer
    European journal of applied physiology 51 (1983), S. 395-408 
    Details
    ISSN: 1439-6327
    Keywords: Isometric exercise ; Intramuscular pressure ; Muscle flow ; Muscle compliance ; Mean voltage EMG
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In five healthy males sustained isometric torques during elbow flexion, knee extension, and plantar flexion correlated positively with intramuscular tissue pressure (MTP) in the range 0–80% of the maximal voluntary contraction (MVC). During passive compression of the muscle at rest 133-Xenon muscle clearance stopped when MTP reached diastolic arterial pressure (DAP) indicating that the muscle vascular bed was occluded. However, during sustained contractions this relation between DAP, flow and MTP was not seen. In two cases 133-Xenon clearance from M. soleus did not stop in spite of an 80% maximal contraction and MTP stayed below DAP. In other cases MTP would reach as high as 240 mm Hg before clearance was zero. In the deeper parts of the muscles MTP during contraction was increased in relation to the more superficial parts. The mean values for the %MVC that would stop MBF varied between 50 and 64% MVC for the investigated muscles. Mean rectified EMG (MEMG) showed a high correlation to MTP during sustained exhaustive contractions: When MEMG was kept constant MTP also remained constant while the exerted force decreased; when force was kept constant both MEMG and MTP increased in parallel. This demonstrated that muscle tissue compliance is decreasing during fatigue. Muscle ischemia occuring during sustained isometric contractions is partly due to the developed MTP, where especially the MTP around the veins in the deeper parts of the muscle can be considered of importance. However, ischemia is also affected by muscle fiber texture and anatomical distorsion of tissues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00429076
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    Paper (German National Licenses)
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