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  • 1985-1989
  • 1980-1984  (175)
  • 1983  (175)
  • Chemical Engineering  (111)
  • Engineering  (35)
  • Rat  (29)
  • Magnetic resonance imaging
  • 1
    Electronic Resource
    Electronic Resource
    Increase of δ-Aminolevulinic Acid Dehydratase (ALAD) in rat erythrocytes in lead poisoning (1983)
    Springer
    Archives of toxicology 52 (1983), S. 1-11 
    Details
    ISSN: 1432-0738
    Keywords: Lead poisoning ; Erythrocytes ; δ-Aminolevulinic acid dehydratase(ALAD) ; Rat ; Porphyrins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The well known fact that the activity of δ-aminolevulinic acid dehydratase (ALAD: EC 4.2.1.24) is reduced in red cells of animals with lead poisoning was found to be upset, by using a modified method of Gibson's original procedure, for determination of activated ALAD activity. The modified method involves addition of 0.2 mM Zn2+ and then preheating the enzyme solution at 60° C for 5 min before following Gibson's original procedure. With this methodological modification, the ALAD activity of erythrocytes of rats poisoned with lead was found increased. Furthermore, the enzyme was purified from the peripheral blood of lead-poisoned rats. ALAD protein in peripheral blood was also determined by single radial immuno diffusion using rabbit anti-serum raised against rat liver ALAD. As the result, the ALAD activity obtained from the modified method was found to be directly proportional to the absolute amount of enzyme proteins determined both by chemically and immunochemically. The modified method for measuring true ALAD content in blood cells in lead poisoning is more reliable than previous ones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00317977
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Early postnatal chlordiazepoxide administration: Permanent behavioural effects in the mature rat and possible involvement of the GABA-benzodiazepine system (1983)
    Springer
    Psychopharmacology 81 (1983), S. 261-266 
    Details
    ISSN: 1432-2072
    Keywords: Chlordiazepoxide ; Postnatal treatment ; Long term behavioural and biochemical effects ; GABA-benzodiazepine receptors ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The long term behavioural and biochemical effects of chronic chlordiazepoxide treatment during the period of neuronal maturation in the rat have been investigated. The administration to lactating mothers of chlordiazepoxide at very low doses (0.22 and 2.6 mg/kg) in their drinking water affects both behavioural and biochemical parameters in offspring at 60 days of age and undrugged since weaning. A deficit in the acquisition of the conditioned avoidance response in treated rats was observed, although no significant difference in spontaneous locomotor activity between control and treated rats was found. 3H-Flunitrazepam binding sites in cerebral cortex and hippocampus were decreased by the treatment, whereas no change was detected in cerebellum. Moreover, 3H-muscimol binding sites increased in hippocampus with no changes in cerebral cortex and cerebellum. According to the different regional distribution of benzodiazepine type 1 and type 2 receptors, we suggest that type 2 receptors are selectively affected by the treatment, and that the GABA ergic receptor system is also permanently altered by administration of chlordiazepoxide during early postnatal life.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427275
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The “accessory body” of Cajal in the neuronal nucleus (1983)
    Springer
    Anatomy and embryology 166 (1983), S. 19-30 
    Details
    ISSN: 1432-0568
    Keywords: Accessory body of Cajal ; Neuronal nucleus ; Neurosecretory cells ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The present light and electron microscopic study deals with the morphology and staining properties of two intranuclear inclusions — the “accessory body” of Cajal and the “coiled body” — in the supraoptic nuclei of adult rat hypothalamus, and supports the assumption that these structures represent the same intrinsic component of the neuronal nucleus. Consequently, we propose to term it “accessory body”. The structure of this body was visualizad by several different staining procedures: conventional electron microscopic techniques, a silver reaction, and the regressive EDTA staining for ribonucleoproteins. The silver-impregnation method employed here, which consists of a silver development sequence on hypothalamic tissue blocks prior to plastic embedding, permitted the study of supraoptic neurons at both light and electron microscopic levels. The nature and origin of “accessory bodies” are suggested and their possible functional role is briefly discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00317942
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  • 4
    Electronic Resource
    Electronic Resource
    Nicotinic cholinoceptor-mediated excitatory postsynaptic potentials in rat nucleus ambiguus (1983)
    Springer
    Experimental brain research 96 (1983), S. 83-88 
    Details
    ISSN: 1432-1106
    Keywords: Fast excitatory postsynaptic potential ; Vagal motoneurons ; Cholinergic interneurons ; Oesophagus ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In rat brainstem slice preparations, intracellular recording from neurons (n = 39) in the compact formation of the nucleus ambiguus (AMBc) revealed spontaneous and miniature excitatory postsynaptic potentials (EPSPs; n = 11) that, along with acetylcholine-induced depolarization, were enhanced by physostigmine (10 μM; n = 2) and blocked by dihydro-β-erythroidine 1–5 pmol (n = 4). Retrograde neuronal tracing combined with choline acetyltransferase immunocytochemistry demonstrated that the AMBc receives a projection from a subpopulation of cholinergic neurons in the zona intermedialis reticularis parvicellularis. Electrical stimulation of this region in slices evoked fast EPSPs in AMBc neurons (n = 23) that were inhibited by dihydro-β-erythroidine 2–5 pmol (n = 8), but not by methscopolamine 1 pmol (n = 2). The present findings strongly support the existence of a cholinergic nicotinic synapse mediating fast transmission in brainstem vagal motoneurons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00230441
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  • 5
    Electronic Resource
    Electronic Resource
    Light- and electron-microscopic study on the maturation of the primary portal plexus during the perinatal period in rats (1983)
    Springer
    Cell & tissue research 234 (1983), S. 179-191 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamo-hypophysial system ; Capillaries ; Ontogenesis ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The maturation of the capillaries of the primary portal plexus in rats during the perinatal period has been studied lightand electronmicroscopically. The number of capillaries covering the median eminence and of those invading the nervous tissue (capillary loops) increases significantly with age. Capillary loops were observed as early as the 18th fetal day. The mitotic divisions of the endothelial cells within the preexisting capillaries seem to be the main reason for the vascular growth. Immature capillaries with a characteristic narrow lumen are surrounded by a fuzzy basal lamina; their wall is formed by a generally expanded endothelium with rather sparse organelles and inclusions, and by minute flattened areas. The maturation of the capillary results in a progressive spread of flattened endothelium followed by an enlargment of the capillary lumen. Moreover, a rising concentration of organelles and inclusions, relatively numerous luminal microvilli, and a dense and uniform basal lamina become noticeable as capillary differentiation proceeds. These data are thought to reflect the progressive increase in the metabolic activity of the endothelium as well as the establishment of capillary patency during the perinatal period of rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217411
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    On extrapolation boundary conditions for the numerical solution of hyperbolic difference schemes (1983)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 19 (1983), S. 1253-1264 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: An analysis is presented for the stability of an initial and boundary value difference scheme arising from the solution of a two-dimensional hyperbolic equation by the Lax-Wendroff method. The positive and negative characteristic speeds of the linear equation are not necessarily equal in magnitude. Supplementary boundary conditions required for the finite difference solution are obtained using extrapolation for a linear combination of the dependent variables. The analysis produces stability intervals for the parameter which describes this linear combination of variables. Numerical experiments are described which support the theoretical analysis.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620190812
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  • 7
    Electronic Resource
    Electronic Resource
    A non-conforming piecewise quadratic finite element on trianglesThis work was partly supported by NSERC and FCAC grant from the Ministère de l'Education du Québec. (1983)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 19 (1983), S. 505-520 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: It is shown in this paper that non-conforming finite elements on the triangle using second-degree polynomials can be easily built and used. Indeed they appear as an ‘enriched’ version of the standard piecewise quadratic six-node element. This work is divided into two parts. In the first we present the basic properties of the element, namely how it can be built and basic error estimates. We also show that this element exhibits a very peculiar regularity property. In the second part we apply our element to the approximation of viscous incompressible flows and more generally to the approximation of incompressible materials.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620190405
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  • 8
    Electronic Resource
    Electronic Resource
    Heat diffusion with time-dependent convective boundary conditionsWork performed under the auspices of the U. S. Department of Energy. (1983)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 19 (1983), S. 1871-1880 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The heating (or cooling) of the rock adjacent to water flowing through a crevice is of interest in certain geothermal studies. For many purposes, only the rock temperature at the rock-water interface is needed. The fact that the convective heat transfer coefficient is a function of time in the case of unsteady flow takes this problem out of the strictly classical domain.Several methods of solution are described. An approach in which the heat equation is solved, under appropriate side conditions, by standard finite difference techniques is shown to be satisfactory but rather wasteful because much unneeded information concerning internal rock temperatures must be obtained. Several integral equations of Volterra type are derived that provide the temperature only at the interface. Two numerical approaches to their solution are described: one quite classical and only partially effective; the other an apparently new algorithm that is fast and efficient. Analytical upper and lower bounds on the temperature are obtained and serve to demonstrate that this numerical device is also very accurate.The algorithm is applicable to a wide class of Volterra integral equations of the second kind. A brief discussion of the possible future uses of this scheme and the need for additional research is given.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620191210
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  • 9
    Electronic Resource
    Electronic Resource
    Pyrolysis of oil shale: Experimental study of transport effects (1983)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 29 (1983), S. 604-610 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The thermal decomposition of kerogen in a Colorado shale was studied in a TGA-type apparatus in which the temperature was first increased at a constant rate and then held constant at a plateau value. Data were obtaiend at plateau temperatures from about 573 to 703 K and at 101.3 kPa.The objective of the research was to determine the influence of transport effects on the observed rate of decomposition. The results show that, for the shale studied, transport of heat and mass influenced the rate, if the particle size was greater than about 0.4 × 10-3 m and if more than two to three layers of particles were placed in the weighing basket.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690290413
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  • 10
    Electronic Resource
    Electronic Resource
    Sedimentation of multisized particles in concentrated suspensions (1983)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 29 (1983), S. 1029-1038 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A model is developed for predicting the sedimentation velocity in suspensions of multisized nonflocculating solids, in which the retarding effect of the smaller particles on the setting velocities of the larger ones is taken into account. Tests of the model, and comparisons with other models, demonstrate that it provides improved prediction of data on suspensions comprising both discrete particle size mixtures and continuous size distributions, and that it is applicable to continuous countercurrent solid-liquid operations.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690290623
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    Paper (German National Licenses)
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