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  • 1990-1994  (8)
  • 1985-1989  (6)
  • 1970-1974
  • 1965-1969
  • 1994  (8)
  • 1985  (6)
  • 1
    Electronic Resource
    Electronic Resource
    Kinetics of Ti(a3F, a5F) and V(a4F, a6D) Depletion by NH3 and H2S (1994)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 98 (1994), S. 13286-13293 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100101a030
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  • 2
    Electronic Resource
    Electronic Resource
    Structures of LuFeO3(ZnO)m (m =1, 4, 5 and 6) (1994)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 50 (1994), S. 332-336 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270193008108
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  • 3
    Electronic Resource
    Electronic Resource
    Synergistic effects of benzalacetone and benzophenone on the electrocrystallization of tin from acid stannous sulphate solutions (1994)
    Springer
    Journal of applied electrochemistry 24 (1994), S. 404-410 
    Details
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract The synergistic effects of two kinds of aromatic ketones (benzalacetone (BA), benzophenone(BP)) and N,N-bis(polyoxyethylene)octadecylamines (POOA) on the surface morphology and the crystal orientation of electrodeposited tin from acid stannous sulphate solutions have been studied by electrochemical methods, scanning electron microscopy and X-ray diffractometry. BA itself had no effect on the reduction of tin (II) ions, but the reduction product of BA had a strong inhibitory effect on the reduction of tin (II) ions. However, the inhibitory effect of BP was stronger than that of the reduction product of BP. POOA induced a uniform deposition of tin over the whole surface, but the crystal grain size and the surface roughness of electrodeposited tin were relatively large. On the other hand, fine-grained and smooth electrodeposited tin, which had a preferred orientation with the (10 0) plane parallel to the surface, were obtained from acid stannous sulphate solutions containing POOA, BA and BP due to the synergistic effects of the three kinds of adsorbed species. It was found that BA has a levelling action and BP has a grain refinement action.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00254152
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  • 4
    Electronic Resource
    Electronic Resource
    Ultrastructural localization of P-glycoprotein on capillary endothelial cells in human gliomas (1994)
    Springer
    Virchows Archiv 425 (1994), S. 133-138 
    Details
    ISSN: 1432-2307
    Keywords: Multi-drug resistance ; P-glycoprotein Human glioma ; Endothelial cells ; Blood-brain barrier
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The P-glycoprotein (P-Gp) encoded by the human multidrug-resistance gene MDR1 has been suggested to play certain roles in the blood-brain barrier (BBB). However, the detailed mechanism of the activity of P-Gp in multidrug-resistance (MDR) remains unclear in human glioma. We examined the localization of P-Gp in human glioma by immunohistochemical (IHC) and immunoelectron microscopic (IEM) methods with anti P-Gp monoclonal antibodies (C219, MRK16). We also examined MDR1 expression in primary glioma and xenografts by reverse transcription-polymerase chain reaction (RT-PCR) with human MDR1-specific primers. The IHC study showed no P-Gp expression on tumour cells but it was present on capillary endothelial cells and IEM analysis showed definitive localization on their luminal surface. MDR1 gene expression was detected in eight primary glioma and three normal brain specimens by RT-PCR, but not in glioma xenografts. The lack of MDR1 expression in these cells appears to be a consequence of the replacement of the original human stroma, including blood vessels, by murine stroma in glioma xenografts. The unique distribution of P-Gp on the capillary blood vessels was confirmed in human glioma by the results of immunohistochemical and molecular biological studies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00230349
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  • 5
    Electronic Resource
    Electronic Resource
    Isolation, growth and characteristics of human ovarian surface epithelium (1994)
    Springer
    Virchows Archiv 424 (1994), S. 59-67 
    Details
    ISSN: 1432-2307
    Keywords: Human ovary ; Ovarian surface epithelium ; Tissue culture ; Growth ; Characterization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The ovarian surface epithelium (OSE) is a key tissue in the pathogenesis of ovarian surface epithelial-stromal tumours and ovarian endometriosis, commonly encountered gynaecological diseases. Despite the high incidence of these diseases, experimental in vitro studies of OSE are few and so we used the scraping method with an enzymatic procedure to isolate human OSE and studied its characteristics in vitro. Nineteen normal ovaries were used. After incubation of the ovary for 40 min in collagenase type 1 solution (300 U/ml), the surface cells were removed by gentle scraping with a surgical blade. Cells obtained as a cluster after unit gravity sedimentation with 5% bovine serum albumin in medium 199 were cultured in medium 199 containing 15% fetal bovine serum. The viable cell number in a single ovary was 0.1−2.7×106. The outgrowth of cells started from a homogeneous population of single cells, and the cell population doubling time was between 7 and 10 days. Confluent monolayers were formed after 13–20 days and subcultured from one to three times. The monolayers mostly had a cobblestone appearance, and fusiform or polygonal cells were also observed. By cytochemistry, immunocytochemistry and scanning and transmission electron microscopy, the cells were shown to have characteristics of mesothelial OSE cells in short-term culture. This experimental approach was efficient in providing cultured human OSE, which can be utilized to investigate pathobiology and carcinogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00197394
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  • 6
    Electronic Resource
    Electronic Resource
    Intra-operative radiation therapy for malignant brain tumours: Rationale, method, and treatment results of cerebral glioblastomas (1994)
    Springer
    Acta neurochirurgica 131 (1994), S. 80-90 
    Details
    ISSN: 0942-0940
    Keywords: Intra-operative radiation therapy ; glioblastoma ; metastatic brain tumour ; radiation therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In radiation therapy for malignant brain tumours, the dose of radiation that can be safely delivered to a tumour is limited by the radiation tolerance of the adjacent normal brain tissue. Among various radiation modalities to produce local tumour eradication without unacceptable complications, we chose a large, single irradiation dose during the operation (intra-operative radiation therapy, IORT). In contrast to X-ray or Cobalt-60 gamma ray irradiation, IORT with a high-energy electron beam delivered by the Shimadzu 20 MeV betatron provides acceptable dose homogeneity with rapid fall-off of the radiation dose beyond the treatment volume. Thus, IORT has the advantage of precise demarcation of the target volume, minimum damage to surrounding normal tissues, and a high absorbed target dose (15–25 Gy in 5–10 min). On the basis of our experience with 170 patients treated by IORT, we established the treatment indications and method in patients with malignant brain tumours. IORT with a dose of 15–25 Gy was delivered to widely resected tumours followed by external radiation therapy. No acute or subacute complications were observed. Treatment results of 30 patients with glioblastoma treated by IORT (mean 18.3 Gy) combined with external radiation therapy (mean 58.5 Gy) resulted in a median survival of 119 weeks and a 2-year survival rate of 61%.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401457
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  • 7
    Electronic Resource
    Electronic Resource
    Muscarinic acetylcholine receptors in rat gastric mucosa (1985)
    Springer
    Histochemistry and cell biology 83 (1985), S. 479-487 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The muscarinic cholinergic innervation of the rat gastric mucosa was investigated by localizing the muscarinic receptors using a tritiated muscarinic antagonist, pirenzepine. Radioautography was performed by freeze drying stomach tissue, which was then embedded in Epon and wet sectioned with ethylene glycol, and dry mounting on emulsion film by the wire-loop method to prevent loss of the labelled substance during fixation and the radioautographic procedure. Light and electron microscopy showed that the specific pirenzepine-binding sites were localized predominantly on parietal cells, chief cells and perivascular plexuses. Analysis of the grain distribution on parietal cells revealed that the silver grains corresponding to the pirenzepine-binding sites were mainly on the basolateral plasma membrane. On the other hand, the surface mucous or mucous neck cells had few pirenzepine-binding sites.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00492448
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  • 8
    Electronic Resource
    Electronic Resource
    Radiation therapy of rat brain tumor using misonidazole as hypoxic cell sensitizer (1985)
    Springer
    Journal of cancer research and clinical oncology 109 (1985), S. 188-192 
    Details
    ISSN: 1432-1335
    Keywords: Experimental nervous system tumor ; Radiation therapy ; Misonidazole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rat brain tumor was used as a model to evaluate radiation therapy with and without misonidazole. BD-IX rats were implanted intracerebrally with an ethylnitrosourea-induced glioma. Three series of experiments were performed, with radiation given 14 days after inoculation of the glioma clone. In each series, the following radiation doses were given: 500 rads once, 1,000 rads once; and 1,000 rads twice, every time with or without two different doses of misonidazole. Radiation therapy significantly prolonged survival when compared to the longevity of the control group. The dose of 1,000 rads given twice was highly effective and the life-span of tumor-bearing rats increased from 72% to 121%. Misonidazole plus irradiation negated the prolongation of survival, achieved with radiation therapy alone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00390355
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  • 9
    Electronic Resource
    Electronic Resource
    A sensitive method for the histochemical demonstration of vicinal diols of carbohydrates (1985)
    Springer
    Journal of molecular histology 17 (1985), S. 477-485 
    Details
    ISSN: 1573-6865
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A new sensitive method has been established for the histochemical demonstration of vicinal diols of carbohydrates in light microscopy. It consists of a periodic acid-thiocarbohydrazide-silver proteinate (PA-TCH-SP) sequence followed by physical development. The new method is more sensitive than the PA-TCH-SP and periodic acid-Schiff (PAS) methods employed hitherto. Its specificity is sufficient.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01003207
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  • 10
    Electronic Resource
    Electronic Resource
    Lack of mutagenicity of fasciolicides (1985)
    Springer
    Veterinary research communications 9 (1985), S. 147-152 
    Details
    ISSN: 1573-7446
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Six fasciolicides, bithionol, bromofenofos, DS-6, nitroxynil, oxyclozanide and tribromsalan, were tested for mutagenicity in theSalmonella reverse mutation test usingS.typhimurium tester strains TA100, TA98, TA153, TA1537 and TA1538 and the micronucleus test in mice. None of the fasciolicides increased the number of revertant colonies in any tester strain in the presence and absence of S9 mix, nor did they induce a significant increase of the micronuclei in erythrocytes. Taking the high correlation between mutagenicity and carcinogenicity into consideration, these results suggest that the fasciolicides tested in this investigation are devoid of carcinogenic action.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02215138
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