ISSN:
1432-0584
Keywords:
Autoimmune thrombocytopenia
;
Platelet glycoproteins
;
Marrow transplantation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary We report the case of a patient who developed autoimmune thrombocytopenia after allogeneic bone marrow transplantation from her HLA-identical sister. An IgG autoantibody was detected that bound to the platelet glycoprotein IIb/IIIa and to the HLA class I proteins. Immunoprecipitation studies with radiolabeled platelets revealed additional antibody binding sites on proteins of 214 kDa molecular weight under nonreduced conditions and 65 and 56 kDa molecular weight under reduced conditions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00320436
Permalink