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  • 1990-1994  (5)
  • 1992  (5)
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  • 1990-1994  (5)
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  • 1
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Correlations between positive pions are investigated in the target fragmentation region of 200A GeV16O+nucleus collisions. The pions are measured with the Plastic Ball detector in the WA80 experiment at the CERN SPS. The target mass dependence of the radii and the correlation strength extracted by interferometry is studied. A new approach to the fit of the correlation function is introduced. The correlation strength and both invariant and transverse radii increase with decreasing target mass. The transverse radius for16O+C reactions appears to be much larger than the geometrical radius of the nuclei involved. For the Au target only a small fraction of the measured pions contributes to the apparent correlation. Hints for a much larger second component in16O+Au reactions are observed. Rescattering phenomena may provide a clue to understand these phenomena.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular evolution 35 (1992), S. 472-485 
    ISSN: 1432-1432
    Keywords: LINE-1 (L1) ; Peromyscus ; Repetitive elements ; Molecular drive
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Two distinct members of the LINE-1 (L1) family in Peromyscus were characterized. The two clones, denoted L1Pm55 and L1Pm62, were 1.5 kb and 1.8 kb in length, respectively, and align to the identical region of the L1 sequence of Mus domesticus. Sequence similarity was on the order of 70% between L1Pm55 and L1Pm62, which approximates that between either Peromyscus sequence and Mus Ll. L1Pm62 represents a more prevalent subfamily than L1Pm55. L1Pm62 exists in about 500 copies per haploid genome, while L1Pm55 exists in about 100 copies. The existence of major and minor subpopulations of L1 within Peromyscus is in contrast to murine rodents and higher primates, where L1 copy number is on the order of 20,000 to 100,000, and where levels of intraspecific divergence among L1 elements are typically less than 15–20%. Additional Peromyscus clones are similarly divergent from both L1Pm62 and LIPm55, implying the existence of more than two distinct L1 subfamilies. The highly divergent L1 subfamilies in Peromyscus apparently have been evolving independently for more than 25 million years, preceding the divergence of cricetine and murine rodents. Investigations of the evolution of L1 within Peromyscus by restriction and Southern analysis was performed using species groups represented by the partially interfertile species pairs P. maniculatus-P. polionotus, P. leucopus-P. gossypinus, and P. truei-P. difficilis of the nominate subgenus and P. californicus of the Haplomylomys subgenus. Changes in L1 and species group taxonomic boundaries frequently coincided. The implications for phylogeny are discussed.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The histamine-receptor subtype mediated effects on action potentials of electrically driven and spontaneously active isolated sheep cardiac Purkinje fibres were investigated using H1-and H2-selective agonists and antagonists. In electrically stimulated Purkinje fibres histamine (3 μmol/l) increased action potential plateau height, decreased action potential duration at −60mV, and enhanced pacemaker activity. These effects were abolished by 30 μmol/l cimetidine (H2-selective antagonist), but not impaired by 0.3 μmol/l dimethindene (H1-selective antagonist). In spontaneously active Purkinje fibres, histamine (10 μmol/l) increased the spontaneous rate by 24%, the slope of diastolic depolarization by 45% and shortened the duration of the diastole at −60mV by 32% of the respective control measurements. These effects were blocked by 30 μmol/l cimetidine, but not by 0.3 μmol/l dimethindene. The concentration-response relationship of histamine was shifted to higher histamine concentrations by approximately 2 logarithmic units in the presence of 30 μmol/l cimetidine, but no displacement was found in the presence of 0.3 μmol/l dimetindene. The H2-selective agonist impromidine (0.001–0.3 μmol/l) has similar actions to histamine on spontaneously active Purkinje fibres, while the H1-selective agonist 2-(2-pyridyl-)ethylamine was ineffective. It is concluded that the pronounced stimulatory action of histamine on spontaneous activity in sheep cardiac Purkinje fibres is exclusively mediated by H2-receptors.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The histamine-receptor-subtype-mediated effects on action potentials of electrically driven and spontaneously active isolated sheep cardiac Purkinje fibers were investigated using H1-and H2-selective agonists and antagonists. In electrically stimulated Purkinje fibers, histamine (3 μmol/l) increased the action potential plateau height, decreased the action potential duration measured at a repolarization level of −60 mV and enhanced the pacemaker activity. These effects were abolished by the H2-selective antagonist cimetidine (30 μmol/l), but were not impaired by the H1-selective antagonist dimetindene (0.3 μmol/l). In spontaneously active Purkinje fibers, histamine (10 μmol/l) increased the spontaneous rate by 24%, the slope of diastolic depolarization by 45% and shortened the duration of the diastole by 32% of the respective control measurements. These effects were blocked by 30 μmol/l cimetidine, but remained unchanged in the presence of 0.3 μmol/l dimetindene. Concentration-response curves of histamine were shifted to the right by approximately 2 logarithmic units in the presence of 30 μmol/l cimetidine, but were not influenced in the presence of 0.3 μmol/l dimetindene. The H2-selective agonist impromidine (0.001–0.3 μmol/l) had similar actions as histamine on spontaneously active Purkinje fibers, while the H1-selective agonist 2-(2-pyridyl-)ethylamine was ineffective. It is concluded that the pronounced stimulatory action of histamine on spontaneous activity in sheep cardiac Purkinje fibers is exclusively mediated by H2 receptors.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Multiplicity and pseudorapidity distributions have been measured for32S+Al, Cu, Ag and Au at 200A GeV. The widths of the pseudorapidity distributions increase from central to peripheral collisions. The main contribution is assumed to come from the increasing fraction of charged particles stemming from the fragmentation of the target for peripheral collisions as compared to central collisions. On the average 170–180 charged particles per unit of pseudorapidity are attained for the most central32S+Au events at the maximum of the distribution. The target dependence of the yield of charged particles for central collisions is investigated. In the target rapidity region the yield is directly proportional to the target mass. The transverse energy per charged particle has been studied as a function of centrality and pseudorapidity. The experimental results are compared to the results from the Monte-Carlo model VENUS 3.11 which includes rescattering among secondaries. A comparison between different centrality triggers is made.
    Type of Medium: Electronic Resource
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