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  • 1995-1999  (5)
  • 1996  (5)
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 136 (1996), S. 0 
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract NAD-glycohydrolase (NADase) was purified from culture supernatant fluids of group C streptococci by adsorption on silica gel, chromatography on hydroxyapatite and ion exchange on Mono S column. After inactivation of a chymotrypsin-like protease, a homogeneous enzyme was isolated with an N-terminal sequence of VSGKEGKKSDVKYEMTKVMEANATSS-KEDKHVMHTLDKVM. According to serological methods, the purified enzyme of group C streptococci was identical to the group A enzyme showing a specific activity of 10000000 U mg−1. It did not attack NADH, NADP or NADPH. In addition, a streptodornase was isolated having an N-terminal sequence of KTVSVNQTYGE.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2102
    Keywords: Schlüsselwörter MRT ; Funktionelle Bildgebung ; Schnelle Sequenzen ; Schnarchen ; OSA ; Key words MRI ; Functional imaging ; Ultrafast sequences ; Snoring ; Obstructive sleep apnea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Functional imaging of the pharynx used to be the domain of cineradiography, CT and ultrafast CT. The development of modern MRI techniques led to new access to functional disorders of the pharynx. The aim of this study was to implement a new MRI technique to examine oropharyngeal obstructive mechanisms in patients with obstructive sleep apnea (OSA). Sixteen patients suffering from OSA and 6 healthy volunteers were examined on a 1.5 T whole-body imager (“Vision”, Siemens, Erlangen Medical Engineering, Germany) using a circular polarized head coil. Imaging was performed with 2D flash sequences in midsagittal and axial planes. Patients and volunteers were asked to breathe normally through the nose and to simulate snoring and the Mueller maneuver during magnetic resonance imaging (MRI). Prior to MRI, all patients underwent an ear, nose and throat (ENT) examination, functional fiberoptic nasopharyngoscopy and polysomnography. A temporal resolution of 6 images/s and an in-plane resolution of 2.67 × 1.8 mm were achieved. The mobility of the tongue, soft palate and pharyngeal surface could be clearly delineated. The MRI findings correlated well with the clinical examinations. We propose ultrafast MRI as a reliable and non-invasive method of evaluating pharyngeal obstruction and their levels.
    Notes: Zusammenfassung Die funktionelle Bildgebung des Pharynx war bisher eine Domäne der Hochfrequenzröntgenkinematographie, der Computertomographie (CT) und der ultraschnellen Computertomographie. Die Entwicklung moderner Techniken in der Magnetresonanztomographie (MRT) führte zu neuen Ansätzen in der Diagnostik pharyngealer Dysfunktionen. Ziel der vorliegenden Studie war die Implementierung neuer schneller MR-Sequenzen, um Verschlußmechanismen entlang des Pharnyxschlauches bei Patienten mit obstruktiver Schlafapnoe (OSA) zu untersuchen. 16 Patienten mit OSA und 6 gesunde Probanden wurden an einem 1,5-T-Ganzkörpermagnetresonanztomographen („Vision“, Siemens Medizintechnik, Erlangen) mit einer zirkularpolarisierten Kopfspule untersucht. Die Bildgebung erfolgte mit schnellen 2D-FLASH-(Fast-low-angle-shot-) Sequenzen in sagittaler und axialer Schichtführung. Patienten und Probanden führten folgende Atemmanöver während der MRT durch: ruhige Nasenatmung bei geschlossenem Mund, Schnarchsimulation und Müller-Manöver. Vor der MRT unterzogen sich die OSA-Patienten einer HNO-ärztlichen Untersuchung, einer funktionellen flexiblen Nasopharyngoskopie und einer Polysomnographie. Mit der 2D-FLASH-Sequenz wurde eine Bildfolge von 6 Bildern/s und eine Ortsauflösung von 2,67 × 1,8 mm erreicht. Die Bewegungen der Zunge, des weichen Gaumens, der Uvula und der Pharynxwände konnten mit Hilfe der MRT dynamisch wiedergegeben werden. Die Darstellung der erhöhten Kollapsneigung der pharyngealen Weichteile bei den OSA-Patienten gelang ebenfalls mit der MRT. Diese Ergebnisse korrelierten gut mit den Untersuchungen der funktionellen flexiblen Nasopharyngoskopie. Die ultraschnelle MRT scheint als zuverlässige, nichtinvasive Methode zur Diagnostik der OSA geeignet zu sein.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Microsystem technologies 2 (1996), S. 130-134 
    ISSN: 1432-1858
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Technology
    Notes: Abstract  For the production of microstructured ceramic parts, development efforts are necessary in the field of powder synthesis as well as in the area of shaping. Several processes have been developed. Powder synthesis was performed starting from metal organic precursors and using a two stage thermal process. Shaping was performed by sol-gel methods, by pressing of a ceramic slurry or an organic precursor paste as well as by direct electrophoretic deposition of gels in a microstructured form. An overview is given on the methods and the results.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Microsystem technologies 2 (1996), S. 135-138 
    ISSN: 1432-1858
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Technology
    Notes: Abstract  The developed process of tape casting with subsequent stamping is a promising way to make three-dimensional ceramic microstructures. Examples of different ceramic materials illustrate, that a good quality of the moulding with high form fit can be attained after optimisation of the slurry and the stamping process. The sintered microstructures are characterised by lateral dimensions in the micron range and high aspect ratios. The unique properties of ceramic materials in combination with this new process can be used to produce microstructured ultrasonic transducers or micro heat exchangers/reactors.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1777
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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