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  • 1
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 70 (1997), S. 931-933 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Stimulated emission at 5.1 μm was demonstrated from a broad area In1−xAlxSb/InSb heterostructure diode laser grown by molecular beam epitaxy. For a 5 μs pulse and a 500 Hz repetition rate the threshold current density was 1480 A cm−2 at 77 K and the maximum operating temperature was 90 K at a current density of 2680 A cm−2. Maximum peak power output was estimated to be 28 mW per facet at 77 K and 4500 A cm−2.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Contradictory reports regarding the ability of complement receptor type 2 (CR2,CD21) on normal B cells to activate complement (C′) via the alternative pathway (AP), prompted us to compare the performance of human peripheral blood B cells and the Epstein–Barr virus-positive Burkitt's lymphoma cell line, Raji (a well characterized AP activator) by using flow cytometry. Measured in terms of the membrane deposition of C3 fragments per cell, Raji cells were significantly (6- to 26-fold) more effective as complement activators than were normal B cells. Raji cells were also found to express approximately four to five times as many CR2 as normal B cells. In addition, they distinguished themselves by displaying a greater Ca2+-dependent activation, with pooled normal human sera (NHS) as the complement source, and by degrading unprotected C3b fragments from iC3b to C3dg/C3d at a significantly lower rate than the B cells. The Ca2+ dependency of Raji cell activation was found to be partially a result of classical pathway (CP) triggering by specific antibodies in the NHS, although other triggering mechanisms may also be involved. If the influence of these variations between Raji cells and normal B cells was excluded, by relating deposition of anti-C3d-reactive fragments, during AP activation, to the number of CR2 expressed, the difference in performance between the two cell types was found to be insignificant.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 24 (1997), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary The aim of this study was to determine the average sagittal condylar inclination angles of dentate subjects using a mandibular facebow with pencil tracing styli, to relate these angles to values assigned to articulators, and to assess the repeatability accuracy of drawing a tangent to a traced curve. The right and left sagittal condylar inclination angles of 103 subjects were recorded using a mandibular facebow with pencil tracing styli which marked a graph card during protrusive excursions. Tangents to the tracings were measured with a protractor allowing assessment of reproducibility. The mean left and right sagittal condylar inclination angles were 32° and 31.5°, respectively, with no significant differences (P=0.609). Individual right and left measurements within each group showed significant differences (P= 0.0000). The mean of the tangents drawn through three sagittal condylar angle tracings by 10 operators was 33.3°, and the mean of 10 tangents drawn through the same three tracings by one of the authors was 32.9°, with no significant difference (P= 0.634). The average sagittal condylar inclination angles found in this study are in agreement with those reported in the literature. In fixed sagittal condylar angle articulators 30° appear to be an appropriate setting. The reproducibility of this method of recording sagittal condylar inclination angles was found to be accurate for the individual operator and between operators.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 53 (1997), S. 105-107 
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: Recombinant rhamnogalacturonase A from Aspergillus aculeatus has been crystallized and X-ray diffraction data has been collected. Crystals were grown by the hanging-drop vapour-diffusion technique, under the conditions 10% PEG 8000, 0.05 M KH2PO4 and 0.1 M sodium acetate buffered at pH 3.5. The crystals diffract beyond 2.0 Å resolution and belong to one of the orthorhombic space groups I212121 or I222, with the unit-cell parameters a = 62.9, b = 125.4 and c = 137.0 Å. There is one molecule in the asymmetric unit and a solvent content of approximately 54%. The enzyme is highly glycosylated corresponding to 5.9 kDa.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 53 (1997), S. 311-315 
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The first crystal structure of an active autolysate form of porcine α-trypsin (APT), a two-chain molecule obtained from the limited autolysis of porcine β-trypsin at position Lys145–Ser146, has been determined. APT crystallizes in space group P212121 with one protein molecule in the asymmetric unit. The structure was solved by molecular replacement followed by refinement using X-PLOR to an R factor of 0.200 and an Rfree of 0.285 for 8.0–1.8 Å data with r.m.s deviations from ideal values of 0.01 Å and 1.7° for bond lengths and bond angles, respectively. Comparison with inactive autolysate porcine ε-trypsin (EPT) and porcine β-trypsin in complex with bittergourd trypsin inhibitor (MCT) revealed a small but systematic directional chain shift around the active-site residues from APT to EPT to MCT.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1434-601X
    Keywords: PACS: 21.10.Hw Spin, parity, and isobaric spin – 23.20.Lv Gamma transitions and level energies – 27.60.+j 90 ≤q A ≤q 149
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: The neutron deficient nucleus 108Te was studied in the 54Fe(58Ni,2p2n) reaction. A detector system consisting of 4 Euroball cluster detectors, a charged-particle detector ball and a 16 element neutron multiplicity filter was used to detect the emitted particles and γ rays. A new, significantly extended level scheme was constructed on the basis of γγ-coincidence relations. Spin values for the states were determined from angular distribution ratios. The experimental results are discussed in terms of the shell model.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1420-9136
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Conclusions Several cases of extremely strong quiescences have been investigated in great detail, and it was found that they are statistically highly significant and that they cannot be reasonably explained by catalog heterogeneity. Several additional cases of quantitatively measured quiescence have been documented. The method of measuring quiescence has progressed from using visual means to using a quantitative approach, and the understanding of the noise sources has significantly advanced during the last few years. Therefore I feel that quiescence is a real phenomenon and the method to detect it has matured to a point that is acceptable for the List of Significant Precursors, although considerably more work needs to be done to understand this parameter and its role in the earthquake generation process.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Surgical endoscopy and other interventional techniques 12 (1998), S. 940-943 
    ISSN: 1432-2218
    Keywords: Key words: Laparoscopic appendectomy—Open appendectomy—Endoscopic linear stapler—Perforated appendicitis—Abscess
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Ever since laparoscopy was first applied to the treatment of appendicitis, a controversy has existed as to whether the acknowledged benefits of a minimally invasive approach warrant its preference over the conventional treatment, which historically has had relatively low morbidity. The purpose of this study was to determine if laparoscopic appendectomy should be performed preferentially in cases where surgeons are not limited by technical constraints. Methods: A retrospective chart review was performed of 112 patients operated on for suspected appendicitis from June 1995 to July 1996. Forty-eight patients underwent laparoscopic appendectomy, and 64 had conventional open appendectomy. Laparoscopic appendectomy was performed using a three-trocar technique and the endoscopic stapler. Results: The histopathological diagnosis of appendicitis was confirmed in 82.6% of cases. Overall, laparoscopic appendectomy reduced length of hospital stay (1.54 versus 4.09 days; p 〈 0.0001) compared to conventional open appendectomy, with no significant difference in hospital cost ($6430 versus $6669; p= ns). Although the total OR time was longer in the laparoscopic group (75.8 versus 60.2 min; p 〈 0.0001), laparoscopy resulted in both a reduction in length of stay (2.17 versus 6.27 days; p 〈 0.0001) and hospital cost ($7506 versus $10,504; p 〈 0.02) for cases of perforated appendicitis. Conversion to open appendectomy was performed in 6% of patients, all of whom had perforated appendicitis. Conclusions: Our data suggest that most cases of acute appendicitis with suspected perforation could be managed laparoscopically. Laparoscopic appendectomy significantly reduces length of stay and hospital costs in patients with perforated appendicitis.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Surgical endoscopy and other interventional techniques 12 (1998), S. 1055-1060 
    ISSN: 1432-2218
    Keywords: Key words: Hiatal hernia — Paraesophageal hernia — Gastroesophageal junction — Esophageal stricture — Collis gastroplasty — Laparoscopic Nissen fundoplication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: The short esophagus increases the difficulty and limits the effectiveness of laparoscopic Nissen fundoplication. In our experience, ∼20–25% of esophagi judged by preoperative criteria to be foreshortened will, after dissection, be insufficiently long to allow 2 cm of esophagus to reside below the diaphragm without inferior distraction (i.e., tension free). Collis gastroplasty combined with Nissen fundoplication has become the standard approach for the creation of an intraabdominal neoesophagus and fundic wrap. Methods: After developing methods of performing totally laparoscopic stapled gastroplasty in the cadaver lab in 1994, we started applying the technique clinically in 1996. We performed 220 laparoscopic antireflux procedures between January 1996 and July 1997. Of these 220 patients, 26% were suspected to have esophageal foreshortening based on preoperative barium studies and/or endoscopy. Results: After hiatal dissection, nine patients, or 16% of those suspected to have esophageal foreshortening and 4% of the entire population, required the laparoscopic Collis-Nissen procedure. There was symptomatic improvement in all patients as assessed by patient-initiated symptom scores. Conclusions: The management of patients with esophageal foreshortening is a complex problem. We believe that our technique of laparoscopic Collis-Nissen provides an effective means of achieving intraabdominal placement of the fundic wrap while maintaining the benefits of a minimally invasive approach.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Journal of inherited metabolic disease 20 (1997), S. 604-605 
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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