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  • 1
    Electronic Resource
    Electronic Resource
    Melanoma-associated paraneoplastic retinopathy: case report and review of the literature (1997)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 137 (1997), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 51-year-old white male suffering from metastatic malignant melanoma of the skin presented with lymph node metastases and paraneoplastic retinopathy 4 years after resection of the primary tumour. There were no cerebral metastases. Ocular symptoms consisting of night blindness and sensations of ‘shimmering lights’ persisted after total resection of the inguinal lymph node metastases and administration of dacarbazine and prednisone. Perimetry of both eyes was abnormal with concentric restriction. Electroretinography showed significantly reduced amplitudes in both eyes. Only 11 patients with melanoma-associated retinopathy (MAR) have been described. High titres of autoantibodies against whole retina extract were detected by enzyme-linked immunosorbent assay (ELISA) reactions. Indirect immunohistochemistry showed strong autoantibody activity against retinal bipolar cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.1997.18701958.x
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  • 2
    Electronic Resource
    Electronic Resource
    Study of surface-emitted stimulated emission in GaN (1997)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 71 (1997), S. 729-731 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report the results of a study of spatially resolved surface-emitted stimulated emission in GaN epilayer samples under conditions of strong optical pumping. We observe that even at excitation powers near the damage threshold, no surface-emitted stimulated emission occurs from samples with a high quality GaN epilayer. In parts of the samples with inferior surface quality, we show that stimulated emission comes from cracks, burned spots, and other imperfections, and is due to the scattering of a photon flux propagating parallel to the surface. Our results suggest that these defects are effective scattering centers and can severely affect the accuracy of optical gain measurements. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.119627
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  • 3
    Electronic Resource
    Electronic Resource
    Is Hylamer adequate for use in alloarthroplasties? (1997)
    Springer
    Archives of orthopaedic and trauma surgery 117 (1997), S. 79-83 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In the present study ultrahigh molecular weight polyethylene (UHMWPE) implants from different manufacturers were evaluated by differential scanning calorimetry (DSC), infrared spectroscopy (IRS) and wide-angle X-ray scattering (WAXS). With DSC measurements the crystallinity of all evaluated implants ranged between 58.2% and 73.2%. The highest crystallinity was documented in Hylamer with 73.2%. These results were checked and confirmed by infrared spectroscopy. According to WAXS studies Hylamer had an orthorhomboid phase as well as a monocline phase. After remelting the orthorhomboid phase was no longer detectable. We do not recommend using UHMWPE implants which have been secondarily modified. The product Hylamer clearly demonstrates how the original crystal structure of UHMWPE can be altered. The described changes in Hylamer implants will probably lead to an increased failure rate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00703447
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  • 4
    Electronic Resource
    Electronic Resource
    Analysis of aminobenzoic acids in waste water from a former ammunition plant with HPLC and combined diode array and fluorescence detection (1997)
    Springer
    Fresenius' journal of analytical chemistry 357 (1997), S. 121-126 
    Details
    ISSN: 1432-1130
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract  Aminobenzoic acids are of major interest in clinical analysis, but their determination in environmental samples has been rarely done. Therefore a method for the determination of 10 aminobenzoic acids in water has been developed, using high-performance liquid chromatography with combined diode array and fluorescence detection. A separation of the analytes has been achieved with a buffer pH 3/methanol gradient. The general elution order has been m-substituted〈p-subst.〈o-subst. aminobenzoic acids. UV and fluorescence data are presented. In a highly polluted water sample of the former ammunition plant Stadtallendorf/Hessen, 4-aminobenzoic acid, 2-amino- benzoic acid and 2-amino-4-nitrobenzoic acid have been detected. After passing a charcoal filter, only the concentration of 4-aminobenzoic acid in a sample from the same site has been above the detection limit. Besides the ten analytes investigated, several unknown compounds have been present in the samples.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002160050124
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  • 5
    Electronic Resource
    Electronic Resource
    Derivatization of aromatic amines for analysis in ammunition wastewater I. Derivatization via bromination of the aromatic ring (1997)
    Springer
    Fresenius' journal of analytical chemistry 357 (1997), S. 909-914 
    Details
    ISSN: 1432-1130
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract  A new derivatization method for aromatic amines is presented based on the bromination of the aromatic ring system in an acetic acid medium to yield bromo derivatives. The derivatization method is very simple to perform and overcomes several problems common in the analysis of polar aromatic amines. The derivatives are easy to extract with pentane and can be separated with gas chromatography. Due to the introduction of the electron withdrawing bromo substituents sensitive detection using an electron capture detector is possible. The method was used to investigate the contents of amino- and aminonitrotoluenes in water samples from the site of a former ammunition plant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002160050273
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  • 6
    Electronic Resource
    Electronic Resource
    Derivatization of aromatic amines for analysis in ammunition wastewater II: Derivatization of methyl anilines by iodination with a Sandmeyer-like reaction (1997)
    Springer
    Fresenius' journal of analytical chemistry 359 (1997), S. 497-501 
    Details
    ISSN: 1432-1130
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract An analytical method for the determination of aromatic amines in water is introduced that uses iodination with a Sandmeyer-like reaction to replace the amino group by iodine in aqueous solution. The non-polar derivatives are extracted with pentane or toluene, separated with gas chromatography and sensitively detected with an ECD. Thirteen major metabolites of nitroaromatic explosives were investigated. The method was used to analyze these metabolites in water samples from the site of a former ammunition plant. The results are compared with the derivatization of aromatic amines via bromination of the aromatic ring.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002160050620
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  • 7
    Electronic Resource
    Electronic Resource
    Towards microbial data integration (1997)
    Springer
    Journal of industrial microbiology and biotechnology 18 (1997), S. 68-72 
    Details
    ISSN: 1476-5535
    Keywords: Keywords: database; integration; microbes; phylogeny
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: There are currently 100–200 microbiology-related databases in existence, although it is impossible to find answers to queries that span even a few of these. The Center for Microbial Ecology (CME) at Michigan State University seeks to change this situation by coordinating the creation of an Integrated Microbial Database (IMD), accessible through the World Wide Web (WWW). Such a system will contain up-to-date phylogeny and taxonomy, gene sequences (including genomes), biochemical data, metabolic models, ecological and phenotypic data. Current main obstacles to creation of an IMD are the lack of a single freely available organismal nomenclature with synonyms and the availability of much critical data. An IMD will have major impacts on microbial biology: currently intractable fundamental questions might be answered, experiments could be refocused, and new commercial possibilities created. An IMD should remain freely available and be created under an open development model.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/sj.jim.2900366
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  • 8
    Electronic Resource
    Electronic Resource
    Comparative analysis of the chromosomal and genomic organization of Ty1-copia-like retrotransposons in pteridophytes, gymnosperms and angiosperms (1997)
    Springer
    Plant molecular biology 33 (1997), S. 11-21 
    Details
    ISSN: 1573-5028
    Keywords: Arabidopsis thaliana ; ferns ; in situ hybridization ; phylogenetics ; pines ; reverse transcriptase genes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We have investigated the physical distribution of the reverse transcriptase genes of Ty1-copia-like retrotransposable elements from 12 plant species belonging to different subdivisions by hybridization in situ on chromosome preparations. Ty1-copia-like elements showed different and non-random hybridization patterns. A dispersed distribution throughout most of the chromosomes with reduced hybridization at some regions or with some weak clustering at other regions was found in Allium cepa, Beta vulgaris, Brassica campestris, Brassica oleracea, Pennisetum glaucum, Pinus elliottii, Selaginella apoda, Vicia faba and Vicia narbonensis. Reduced hybridization occured mainly at centromeric regions, nucleolus-organizing regions and regions known to be mainly composed of tandemly repeated sequences. In the fern Pteris cretica the retroelements showed a dispersed genomic organization with clustering at some chromosomal regions and whole chromosomes showing little signal. In Arabidopsis thaliana and Cicer arietinum, Ty1-copia-like elements were found in clusters at the paracentromeric heterochromatin, a novel organization for a repetitive element in A. thaliana. New retroelement families were isolated from A. thaliana and from Beta vulgaris. Alignment of the deduced peptide sequences with Ty1-copia-like elements from other plants showed considerable divergence which was used to calculate their relationships, indicating the value of reverse transcriptase gene analysis in phylogenetic and biodiversity studies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1005797222148
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  • 9
    Electronic Resource
    Electronic Resource
    Myocardial K homeostasis in ischemia-importance of Na,K-ATPase (1997)
    Springer
    Basic research in cardiology 92 (1997), S. 57-59 
    Details
    ISSN: 1435-1803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusions Myocardial and skeletal muscular K homeostasis is of importance for the integrity of myocardial function. Myocardial K homeostasis is affected by ischemia. Cardiac failure as well as diuretic therapy may individually and combined lead to dysfunction of K homeostasis. ACE inhibitors and β-adrenoceptor antagonists can beneficially affect K homeostasis explaining the decrease in mortality seen in heart failure patients treated with such drugs. Knowledge concerning the regulation of Na,K-ATPase and its link to K handling may render new insight in the pathophysiology of cardiac disease, and may hence lead to novel therapeutic interventions based on a rational approach.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00797212
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  • 10
    Electronic Resource
    Electronic Resource
    Detection of alien chromatin conferring resistance to the beet cyst nematode (Heterodera schachtii Schm.) in cultivated beet (Beta vulgaris L.) using in situ hybridization (1997)
    Springer
    Chromosome research 5 (1997), S. 186-193 
    Details
    ISSN: 1573-6849
    Keywords: Beta species ; marker-assisted selection ; molecular cytogenetics ; nematode resistance ; satellite DNA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Chromatin originating from wild beets of the genus Beta, section Procumbentes, has been investigated in nematode-resistant hybrid-derived lines of sugar beet (Beta vulgaris L.) by in situ hybridization using satellite, telomeric and ribosomal DNA repeats, a yeast artificial chromosome (YAC) and total genomic DNA as probes. The alien chromosome was detected in three monosomic addition lines(2n=18+1) by genomic in situ hybridization. Fluorescence in situ hybridization with a genome-specific satellite repeat and YAC DNA enabled the visualization of Procumbentes chromosomes, and in double-target hybridization it was shown that they do not carry 18S–5.8S–25S rRNA and 5S rRNA genes. The wild beet-specific satellite repeat and the telomere sequence from Arabidopsis thaliana were used to perform a structural analysis of the wild beet chromosome fragments of two resistant fragment addition lines. It was shown that one physical end of the chromosome fragments consists of telomeric repeats. Comparison of fragment sizes indicated that the small chromosome fragments harbouring the resistance gene most likely resulted from the loss of one wild beet chromosome arm and an internal deletion of the remaining arm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018447031020
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