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  • 2000-2004  (2)
  • 2000  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Accreditation and quality assurance 5 (2000), S. 95-99 
    ISSN: 1432-0517
    Keywords: Key words Certified reference materials ; Uncertainty ; Characterisation ; Uncertainty analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract  Certification of reference materials is far more than just characterisation of a selected homogeneous batch of material. From the perspective of the ISO Guide on the Expression of Uncertainty in Measurement (GUM) all uncertainty sources relevant to the user of an individual certified reference material (CRM) sample at a moment in time should be part of the CRM uncertainty. This not only includes the full uncertainty of the batch characterisation (rather than the statistical variation), but also all uncertainties related to possible between-bottle variation, instability upon long-term storage and instability during transport to the customer.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    ISSN: 1432-1130
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Uncertainties of four enzyme-CRMs that have recently been certified in a co-operation between the IRMM and the International Federation for Clinical Chemistry were estimated. Estimation was based on the sum of the uncertainties of characterization, homogeneity and stability. Data from the certification collaborative study were used to estimate laboratory uncertainties, which form the basis for the uncertainty of characterization. Estimations for the uncertainty of homogeneity were derived from classical homogeneity studies. The estimations of uncertainty of stability caused the most difficulties. Realistic uncertainties fitting the needs of customers while being derived from measurement data based on theoretical considerations were obtained.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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