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  • 2000-2004  (42)
  • 1985-1989
  • 1945-1949
  • 1925-1929
  • 1880-1889
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  • 2002  (42)
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  • 2000-2004  (42)
  • 1985-1989
  • 1945-1949
  • 1925-1929
  • 1880-1889
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  • 1
    Electronic Resource
    Electronic Resource
    The effects of fungal inoculum arrangement (scale and context) on emergent community development in an agar model system (2002)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology ecology 39 (2002), S. 0 
    Details
    ISSN: 1574-6941
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Consequences of initial spatial organisation of model fungal communities upon their spatio-temporal development were investigated. Dynamics of prescribed two- and three-species ‘communities’ developing on tessellated agar tile model systems were analysed in terms of literal maps, principal component analyses, or as the proportion of species extant within tiles. It was established that for two-species interactions of equal patch size, large-scale (i.e. many constituent tiles) behaviour could be extrapolated from the relevant small-scale (i.e. pairs of tiles) interactions. However, relative patch sizes (scale) of species within tessellations influenced the times taken by individuals to colonise tiles and, hence, temporal behaviour of the system. Outcome of arrangements involving three species of equal patch size and inoculum potential, and prescribed with different mixing patterns, could not be directly extrapolated by reference to the outcome of pair-wise interactions between constituent species. Three-species arrangements attempt to limit assembly of lateral aggregates of individuals (patch size) and hence any effects of tile colonisation times, so as to reveal effects of nearest neighbour context within the complex community. Such arrangements indicate that spatial configuration of inoculum influences community development and reproducibility. They also suggest that spatial distribution of species affects persistence of individuals, which would otherwise be expected to be eliminated from the system. Two-species interactions appeared generally more reproducible than those comprising three species, and the sensitivity of fungal community development to temperature was not solely associated with influence on colony extension rate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6941.2002.tb00901.x
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  • 2
    Electronic Resource
    Electronic Resource
    Proteome Analysis of Highly Immunoreactive Proteins of Helicobacter pylori (2002)
    Oxford, UK : Blackwell Science Ltd
    Helicobacter 7 (2002), S. 0 
    Details
    ISSN: 1523-5378
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background. Identification of the immunoreactive proteins of Helicobacter pylori is important for the development of both diagnostic tests and vaccines relating to the organism. Our aim was to determine whether there are significant differences between human IgG and IgA reactivities to individual H. pylori proteins, and whether patterns of immunoreactivity are sustained across different strains of H. pylori.Method. The total complement of protein from seven strains of H. pylori was resolved by two-dimensional polyacrylamide gel electrophoresis (2D-PAGE). Proteins were transferred electrophoretically onto polyvinylene difluoride (PVDF) membranes, which were probed with sera pooled either from H. pylori-infected patients, or noninfected (control) patients. Highly immunoreactive proteins were detected using chromogenic enzyme-antibody conjugates recognising either serum IgG or IgA. These proteins were then characterised by tryptic peptide-mass fingerprinting using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS).Results. Highly immunoreactive proteins were detected which were common to all seven strains, and recognised by both immunoglobulin subclasses. The proteins appear to be localised in five groups. Protein analysis established that these groups encompass multiple isoforms of chaperonin HspB (two subgroups); urease β-subunit UreB; elongation factor EF-Tu; and flagellin FlaA. The pattern of highly immunoreactive proteins was strongly conserved across the seven strains.Conclusion. These results suggest that within a tightly defined region on the H. pylori proteome map there are five groups of proteins that are highly reactive to both IgG and IgA. Our analysis suggests it is unlikely that the highly immunoreactive clusters harbour any significant proteins other than isoforms of HspB, UreB, EF-Tu and FlaA, and that, with the partial exception of FlaA, these clusters are strongly conserved across all seven strains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1523-5378.2002.00078.x
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  • 3
    Electronic Resource
    Electronic Resource
    Acute administration of cocaine regulates the phosphorylation of serine-19, -31 and -40 in tyrosine hydroxylase (2002)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 82 (2002), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Acute cocaine can inhibit catecholamine biosynthesis by regulating the enzymatic activity of tyrosine hydroxylase via alterations in the phosphorylation state of the enzyme. The mechanisms underlying acute cocaine-dependent regulation of tyrosine hydroxylase phosphorylation have not been determined. In this study, 0, 15 or 30 mg/kg cocaine was administered intraperitoneally to rats and the phosphorylation state of tyrosine hydroxylase in the brain was examined using antibodies specific for the phosphorylated forms of serine-19, -31 and -40 in tyrosine hydroxylase. In the caudate and nucleus accumbens, cocaine dose-dependently decreased the levels of phosphorylated serine-19, -31 and -40. In the ventral tegmental area, the levels of phosphorylated serine-19, but not serine-31 and -40, were decreased by 15 and 30 mg/kg cocaine. In the amygdala, the levels of phosphorylated serine-19, but not serine-31 or -40, were decreased. The functional effects of these alterations in phosphorylation state were assessed by measuring tyrosine hydroxylase activity in vivo(accumulation of DOPA after administration of the decarboxylase inhibitor NSD-1015). Acute administration of 30 mg/kg cocaine significantly decreased l-DOPA production in caudate and accumbens but not in amygdala. These data suggest that the phosphorylation of serine-31 or -40, but not serine-19, is involved in the regulation of tyrosine hydroxylase activity by acute cocaine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.2002.00982.x
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  • 4
    Electronic Resource
    Electronic Resource
    Species differences in the expression of multiple tyrosine hydroxylase protein isoforms (2002)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 81 (2002), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In subprimates, a single form of tyrosine hydroxylase (TH) is expressed, whereas two TH protein isoforms have been identified in monkeys and four isoforms have been demonstrated in humans. In order to establish the evolutionary pattern/emergence of these multiple TH isoforms, adrenal medullae from different mammalian species were analyzed by blot immunolabeling using pan-specific TH antibodies and antibodies specific to each of the four human TH isoforms. The expression of multiple TH isoforms was primate specific and restricted to anthropoids: only a single TH isoform was detected in adrenal medullae from several subprimate and prosimian species (six species from four families), while two TH isoforms were found in all of the anthropoid species studied. The presence of four TH isoforms could only be demonstrated in human specimens. Contrary to previous suggestions, only one TH protein isoform was found in rats and only four TH protein isoforms were found in humans.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.2002.00881.x
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  • 5
    Electronic Resource
    Electronic Resource
    Phase Transformations of Plasma-Sprayed Zirconia–Ceria Thermal Barrier Coatings (2002)
    Westerville, Ohio : American Ceramics Society
    Journal of the American Ceramic Society 85 (2002), S. 0 
    Details
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Phase constituents and transformations of plasma-sprayed thermal barrier coatings (TBCs) with CeO2-stabilized ZrO2 (CSZ; 16–26 wt% CeO2) have been investigated using X-ray diffractometry (XRD), scanning electron microscopy (SEM), and energy-dispersive spectroscopy (EDS). The as-coated CSZ coatings with 16 and 18 wt% CeO2 consisted only of the nonequilibrium tetragonal (t′) phase. A mixture of the t′ and the nonequilibrium cubic (c′) phases was observed for the as-coated CSZ coatings containing 20–26 wt% CeO2. During 65 min cyclic oxidation at 1135°C (45 min hold time) in air, the t′ or the mixture of the t′ and the c′ phases decomposed to the equilibrium tetragonal (t) and the equilibrium cubic (c) phases. Some of the t phase transformed to the monoclinic (m) phase on cooling. More m phase was observed to develop in the CSZ coating containing 16 wt% CeO2 than in the other coatings. More m phase was observed on the top surface than on the bottom surface of the CSZ coating. Spalling of the plasma-sprayed CSZ coating during thermal cycling occurred after 230 cycles for the CSZ coating containing 16 wt% CeO2, whereas the lifetime of the CSZ coatings with 18–26 wt% CeO2 ranged between 320 and 340 cycles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1151-2916.2002.tb00405.x
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  • 6
    Electronic Resource
    Electronic Resource
    Effect of Oxidation on Mechanical Properties of Fibrous Monolith Si3N4/BN at Elevated Temperatures in Air (2002)
    Westerville, Ohio : American Ceramics Society
    Journal of the American Ceramic Society 85 (2002), S. 0 
    Details
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The oxidation behavior and its effect on the mechanical properties of fibrous monolith Si3N4/BN after exposure to air at temperatures ranging from 1000° to 1400°C for up to 20 h were investigated. After exposure at 1000°C, only the BN cell boundary was oxidized, forming a B2O3 liquid phase. With increasing exposure temperature, the Si3N4 cells began to oxidize, forming crystalline Y2Si2O7, SiO2, and silicate glass. However, in this case, a weight loss was observed due to extensive vaporization of the B2O3 liquid. After exposure at 1400°C, large Y2Si2O7 crystals with a glassy phase formed near the BN cell boundaries. The oxidation behavior significantly affected the mechanical properties of the fibrous monolith. The flexural strength and work-of-fracture decreased with increasing exposure temperature, while the noncatastrophic failure was maintained.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1151-2916.2002.tb00597.x
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  • 7
    Electronic Resource
    Electronic Resource
    Fabrication of Macrochannelled-Hydroxyapatite Bioceramic by a Coextrusion Process (2002)
    Westerville, Ohio : American Ceramics Society
    Journal of the American Ceramic Society 85 (2002), S. 0 
    Details
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A coextrusion process was used to fabricate macrochannelled hydroxyapatite (HA). To improve the powder characteristics, the HA powder was calcined at 900°C in air for 1 h. A feedrod composed of HA (shell) and carbon black (core) was coextruded at 120°C through a symmetric 8:1 square reduction die. After the first coextrusion, the individual pieces were bundled, warm-pressed, and then coextruded again. After removing the binder, the billet was sintered at 1350°C for 1h in air. Uniform, 27 vol% macrochannels with a diameter of 270 μm were formed in the dense HA through removal of the carbon black. The compressive strength of the test specimens was strongly dependent on the macrochannel direction due to the stress concentrations related to the macrochannel geometry.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1151-2916.2002.tb00500.x
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  • 8
    Electronic Resource
    Electronic Resource
    Innovations in Integrity-Based Personnel Selection: Building a Technology-Friendly Assessment (2002)
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    International journal of selection and assessment 10 (2002), S. 0 
    Details
    ISSN: 1468-2389
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: We are currently observing a paradigm shift in the composition of personnel selection inventories from lengthy paper-and-pencil administration and scoring to innovative applications of information technology. These technological advances have been driven primarily by strong demands from human resource professionals for enhancements in speed, effectiveness, and cost containment. In response, an existing pre-employment selection assessment was modified to make it more concise, economical, and ‘technology-friendly’. The resulting integrity-based assessment system, the Applicant Potential Inventory or API (London House 1997), has been administered and scored using a wide variety of technologies, including telephone, personal computer, fax, and the Internet. This article describes the initial development of the API and reviews nine field studies conducted to examine its reliability, validity, fairness, and financial impact.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1468-2389.00195
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  • 9
    Electronic Resource
    Electronic Resource
    Parliamentary Election Turnout in Europe since 1990 (2002)
    108 Cowley Road, Oxford OX4 1JF, UK : Blackwell Publishers Ltd.
    Political studies 50 (2002), S. 0 
    Details
    ISSN: 1467-9248
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Political Science
    Notes: This article examines the cross-national variations in turnout for parliamentary elections in Europe since 1990 – a continent with a vast range in turnout levels and some clear subregional patterns, especially that of low turnout in East-Central Europe. A full range of socio-economic, mobilizational, party system, institutional, and contextual factors are examined for bivariate relationships with turnout. A multivariate model then indicates that cross-national turnout is higher where there is strictly enforced compulsory voting, in polarized two-party systems and countries with a high level of party membership, and where there are no relevant elected presidents or strong regional governments. Variances on these and other key factors are what accounts for the subregional pattern of East-Central Europe and the highest turnout case of Malta; however, Switzerland is confirmed to be a significant national dummy variable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1467-9248.00400
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  • 10
    Electronic Resource
    Electronic Resource
    DISCUSSION (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 38 (2002), S. 0 
    Details
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1752-1688.2002.tb01554.x
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