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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 90 (2001), S. 509-511 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Cobalt (Co) nanowire arrays were electrodeposited into the pores of polycarbonate membranes. A magnetic field parallel or perpendicular to the membrane plane was applied during deposition to control the wire growth. X-ray diffraction, transmission electron microscopy, and vibrating sample magnetometer were employed to investigate the structure as well as the magnetic properties of the nanowire arrays. The results show that the magnetic field applied during deposition strongly influences the growth of Co nanowires, inducing variations in their crystalline structure and magnetic properties. The sample deposited with the field perpendicular to the membrane plane exhibits a perpendicular magnetic anisotropy with greatly enhanced coercivity and squareness as a result of the preferred growth of Co grains with the c axis perpendicular to the film plane. In contrast, the deposition in a parallel magnetic field forces Co grains to grow with the c axis parallel to the film plane, resulting in in-plane anisotropy. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 9 (2002), S. 3558-3566 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Recent spectroscopic analysis of charged particles generated by fusion reactions in direct-drive implosion experiments at the OMEGA laser facility [T. R. Boehly et al., Opt. Commun. 133, 495 (1997)] show the presence of low-mode-number asymmetries in compressed-capsule areal density (ρR) at the time of fusion burn. Experiments involved the acquisition and analysis of spectra of primary (14.7 MeV) protons, from capsules filled with deuterium and helium-3, and secondary (12.6–17.5 MeV) protons, from cryogenic deuterium capsules. The difference between the birth energy and measured energy of these protons provides a measure of the amount of material they passed through on their way out of a capsule, so measurements taken at different angles relative to a target provide information about angular variations in capsule areal density at burn time. Those variations have low-mode-number amplitudes as large as ±50% about the mean (which is typically ∼65 mg/cm2); high-mode-number structure can lead to individual pathlengths through the shell that reach several times the mean. It was found that the observed ρR asymmetries are often similar for contiguous implosions, but change when the laser beam energy balance is significantly changed, indicating a direct connection between drive symmetry and implosion symmetry. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 5106-5117 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Spectral measurements have been made of charged fusion products produced in deuterium + helium-3 filled targets irradiated by the OMEGA laser system [T. R. Boehly et al., Opt. Commun. 133, 495 (1997)]. Comparing the energy shifts of four particle types has allowed two distinct physical processes to be probed: Electrostatic acceleration in the low-density corona and energy loss in the high-density target. When the fusion burn occurred during the laser pulse, particle energy shifts were dominated by acceleration effects. Using a simple model for the accelerating field region, the time history of the target electrostatic potential was found and shown to decay to zero soon after laser irradiation was complete. When the fusion burn occurred after the pulse, particle energy shifts were dominated by energy losses in the target, allowing fundamental charged-particle stopping-power predictions to be tested. The results provide the first experimental verification of the general form of stopping power theories over a wide velocity range. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 2578-2584 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Recent work has resulted in the first high-resolution, spectroscopic measurements of energetic charged particles on OMEGA laser facility [T. R. Boehly et al., Opt. Commun. 133, 496 (1997)]. Energy spectra of charged fusion products have been obtained from two spectrometers, and have been used to deduce various physical quantities in imploded capsules. In this paper the first use of 14.7 MeV deuterium–helium3 (D–3He) proton spectra for diagnosing shell areal density (ρR) and fuel ion temperature (Ti) is discussed. For thick-plastic shell capsules, shell areal densities between 20 and 70 mg/cm2 and ion temperatures between 3 and 5 keV have been determined. The spectral linewidths associated with such capsules are found to be wider than the doppler widths. This effect, the focus of future study, is the result of ρR evolution during the burn; or is the result of an extended burn region; or results from nonuniformities in the shell. For thin-glass shell capsules, the spectral linewidths are dominated by the doppler width, and ion temperatures between 10 and 15 keV were determined. These measurements have been also compared and contrasted with the results from neutron measurements and from one-dimension hydrodynamic simulations. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 8 (2001), S. 606-610 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Fast protons (approximately-greater-than)1 MeV have been observed on the 60-beam, 30 kJ OMEGA laser [T. R. Boehly et al., Opt. Commun. 133, 495 (1997)] at an intensity I(similar, equals)1015 W/cm2 and a wavelength λ=0.35 μm. These energies are more than 5 times greater than those observed on previous, single-beam experiments at the same Iλ2. The total energy in the proton spectrum above 0.2 MeV is ∼0.1% of the laser energy. Some of the proton spectra display intense, regular lines which may be related to ion acoustic perturbations in the expanding plasma. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Implosions of direct-drive, deuterium–tritium (DT) gas-filled plastic capsules are studied using nuclear diagnostics at the OMEGA laser facility [T. R. Boehly et al., Opt. Commun. 133, 495 (1997)]. In addition to traditional neutron measurements, comprehensive sets of spectra of deuterons, tritons, and protons elastically scattered from the fuel and shell by primary DT neutrons ("knock-on" particles) are, for the first time, obtained and used for characterizing target performance. It is shown with these measurements that, for 15-atm DT capsules with 20-μm CH shells, improvement of target performance is achieved when on-target irradiation nonuniformity is reduced. Specifically, with a two-dimensional (2D) single-color-cycle, 1-THz-bandwidth smoothing by spectral dispersion (SSD), plus polarization smoothing (PS), a primary neutron yield of ∼1×1013, a fuel areal density of ∼15 mg/cm2, and a shell areal density of ∼60 mg/cm2 are obtained; these are, respectively, ∼80%, ∼60%, and ∼35% higher than those achieved using 0.35-THz, 3-color-cycle, 2D SSD without PS. (In determining fuel areal density we assume the fuel to have equal numbers of D and T.) With full beam smoothing, implosions with moderate radial convergence (∼10–15) are shown to have ρR performance close to one-dimensional-code predictions, but a ratio of measured-to-predicted primary neutron yield of ∼0.3. Other capsules that are predicted to have much higher radial convergence (3.8-atm DT gas with 20-μm CH shell) are shown to have ρRfuel∼3 mg/cm2, falling short of prediction by about a factor of 5. The corresponding convergence ratios are similar to the values for 15-atm capsules. This indicates, not surprisingly, that the effects of mix are more deleterious for high-convergence implosions. A brief comparison of these moderate- and high-convergence implosions to those of similar deuterium–deuterium (D2) gas-filled capsules shows comparable hydrodynamic performance. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The basis for a time-of-flight neutron spectrometer for inertial confinement fusion (ICF) experiments using recoils from a shaped scattering foil is presented. It is shown that the number of elastic recoils can be substantially increased by utilizing a large scattering foil in the shape of an ellipsoid, with the curvature of the ellipsoid being determined by the mass of the recoil particle. This shape allows the time-of-flight dispersion — present originally in the neutrons — to be maintained in the recoils despite the large foil area. The feasibility of using this design on current ICF experiments is discussed. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: With charged-particle spectroscopy implemented on OMEGA, we have been able to routinely measure the particle spectra (both nuclear lines and continua) from a variety of capsule implosions. Important parameters such as fusion yields, fuel and shell areal densities, and ion temperatures can be readily deduced. We will report on details of this work with emphasis on the implosion physics. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A model independent method to determine fuel 〈ρR〉 is to measure the energy spectrum and yield of elastically scattered primary neutrons in deuterium–tritium (DT) plasmas. As is the case for complementary methods to measure fuel 〈ρR〉 (in particular from knock-on deuterons and tritons [S. Skupsky and S. Kacenjar, J. Appl. Phys. 52, 2608 (1981); C. K. Li et al. (unpublished)]), minimizing the background is critical for successful implementation. To achieve this objective, a novel spectrometer for measurements of neutrons in the energy range 10–18 MeV is proposed. From scattered neutrons (10–13 MeV), the DT fuel 〈ρR〉 will be measured; from primary neutrons (∼14 MeV), the ion temperature and neutron yield will be determined; and from secondary neutrons, in the energy range 12–18 MeV, the fuel 〈ρR〉 in deuterium plasmas will be inferred at the National Ignition Facility. The instrument is based on a magnetic spectrometer with a neutron-to-deuteron (nd) conversion foil for production of deuteron recoils at nearly forward scattered angles. In its initial phase of implementation, CR-39 track detectors will be used in the focal plane to detect the recoil deuterons with extremely high spatial resolution. Besides simplicity, CR-39 track detectors will facilitate a highly accurate energy calibration. However, in a later implementation of the spectrometer design, the recoils will also be detected by an array of fast scintillation counters functioning in current mode. In either detection scheme, the detection efficiency is about 10−9 for measuring 14 MeV neutrons with an energy resolution of about 3%. Due to its large dynamic range, its relatively high efficiency, and a compliant design that allows for significant background rejection, this spectrometer can be effectively used, with very high resolution, at both OMEGA and the National Ignition Facility. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK; Malden, USA : Blackwell Publishing Ltd/Inc.
    Wound repair and regeneration 13 (2005), S. 0 
    ISSN: 1524-475X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Sepsis remains the single most important cause for multiple organ failure and death following burn injury for which no effective treatment is currently available. Burn injury is associated with immunosuppression which promotes sepsis. Studies from our laboratory have demonstrated that levels of the antimicrobial peptide (AMP), human β-defensin-2, was significantly decreased in burned skin epithelia, absent in burn blister fluid and poorly expressed in lung during inhalation injury.We hypothesize that 1) deficient antimicrobial peptides in burn wound promote progressive colonization of pathogens in burn wounds and 2) replacing active peptide components will restore the antimicrobial activity in burn wounds. We have synthesized several cationic steroid antimicrobials (CSAs) which mimic naturally occurring AMPs functionally. In vitro experiments using one of these synthetic drugs with locally isolated common burn pathogen P. aeruginosa and S aureus demonstrate MIC values of 2.0 ± 0.3 μg/ml and 0.4 ± 0.1 μg/ml, respectively, indicating effectiveness of these compounds against burn pathogens. These drugs were tested for cytotoxicity on cultured human keratinocytes using MTT cell viability assay. Results indicate that these drugs are nontoxic to cultured keratinocytes at the level required for bacterial killing. Since theses drugs are membrane active compounds it will be hard for bacteria to develop resistance and there is a great potential to be developed for clinical treatment.
    Type of Medium: Electronic Resource
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