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  • 2005-2009  (1)
  • 1995-1999  (3)
  • 1990-1994  (12)
  • 1970-1974  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Gas chromatography-olfactometry of orange juice to assess the effects of plastic polymers on aroma character (1992)
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 40 (1992), S. 650-654 
    Details
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jf00016a026
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  • 2
    Electronic Resource
    Electronic Resource
    Molecular marker-assisted selection for development of common bean lines resistant to angular leaf spot (2005)
    Berlin, Germany : Blackwell Verlag GmbH
    Plant breeding 124 (2005), S. 0 
    Details
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The objective of this work was to develop homozygous common bean lines carrying angular leaf spot resistance genes derived from the cultivars ‘Mexico 54’, ‘MAR 2’ and ‘BAT 332’ through marker-assisted selection. Molecular markers SCAR OPN02890, RAPD OPE04500 and OPAO12950 linked to the resistance genes of ‘Mexico 54’, ‘MAR 2’ and ‘BAT 332’, respectively, were used in segregating backcross-derived populations to selection. DNA fingerprinting was used to select homozygous BC2F3 and BC1F3 resistant plants genetically closer to the recurrent parent. Two homozygous BC2F2:3 and two and five BC1F2:3 families derived from ‘Ruda’ vs. ‘Mexico 54’ (RM), ‘MAR 2’ (RMA) and ‘BAT 332’ (RB) crosses were selected, respectively. After only one (RMA, RB) or two backcrosses (RM), five and eight BC1F3 lines derived from RMA and RB, respectively, and seven BC2F3 lines derived from RM, with 14.9–16.6, 16.9–18.6 and 9.3–11.1% of relative genetic distances to the recurrent parent were selected. This is the first report of lines resistant to angular leaf spot carrying genes of the cultivars ‘Mexico 54’, ‘MAR 2’ and ‘BAT 332’ developed with the aid of molecular markers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0523.2005.01155.x
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  • 3
    Electronic Resource
    Electronic Resource
    Bi12(Bi0.5IIITl0.5III)O19.50 (1994)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 50 (1994), S. 656-659 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270193011205
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  • 4
    Electronic Resource
    Electronic Resource
    Applying Lagrangian relaxation to the resolution of two‐stage location problems (1999)
    Springer
    Annals of operations research 86 (1999), S. 179-198 
    Details
    ISSN: 1572-9338
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Notes: Abstract A family of two‐stage location problems is considered. These problems involve a systemproviding a choice of depots andyor plants, each with an associated location cost, and a setof demand points which must be supplied, in such a way that the total cost is minimized. Byusing Lagrangian relaxation, lower bounds and heuristic solutions are obtained for two kindsof formulation involving two or three indexes for each transportation variable. The goodnessof both formulations is compared by means of a computational study, and the results forseveral instances are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018998500803
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  • 5
    Electronic Resource
    Electronic Resource
    Transfer of secondary metabolites from the spongesDysidea fragilis andPleraplysilla spinifera to the mantle dermal formations (MDFs) of the mudibranchHypserlodoris webbi (1994)
    Springer
    Cellular and molecular life sciences 50 (1994), S. 510-516 
    Details
    ISSN: 1420-9071
    Keywords: Nudibranch ; Hypselodoris ; sponge ; Dysidea ; Pleraplysilla ; Microciona ; furanosesquiterpenoids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The opisthobranch molluscHypselodoris webbi is able to select, among its potential preys, sponges chemically rich in furanosesquiterpenoids. The sequestered secondary metabolites act as defensive allomones against predators and are accumulated in some dorsal glands (MDFs). This transfer from sponges to MDFs has been proven by maintainingH. webbi together with some selected sponges in an aquarium for a prolonged period.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01920760
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  • 6
    Electronic Resource
    Electronic Resource
    Dinucleotides and G + C content in human genes: Opposite behavior of GpG, GpC, and TpC at II-III codon positions and in introns (1993)
    Springer
    Journal of molecular evolution 37 (1993), S. 131-136 
    Details
    ISSN: 1432-1432
    Keywords: Human genome ; Dinucleotides ; Introns ; II-III codon positions ; G + C content
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We have studied the behavior of the dinucleotide preferences under G + C content variation in human genes. The doublet preferences for each dinucleotide were compared between two functionally distinct zones in genes, the II-III codon positions, and the introns. The 16 dinucleotides have been tentatively classified in three groups: AA, AC, CC, CT, and GA, doublets showing no difference between introns and II-III codon positions in the full range of G + C variation TG and TA, which differ in the full range of G + C variation AT, AG, GT, TC, TT, GG, GC, CG, and CA, which show differences in regions over 50% G + C A remarkable pattern observed concerns the behavior of GG, GC, and TC, which showed opposite trends in II-III codon positions and in introns. If codon positions and introns are under the same structural requirements and the same mutational bias, our results indicate that the differences observed could be related to post-transcriptional constraints acting on mRNA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02407348
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  • 7
    Electronic Resource
    Electronic Resource
    A randomized study of mitoxantrone plus cytarabine versus daunomycin plus cytarabine in the treatment of previously untreated adult patients with acute nonlymphocytic leukemia (1994)
    Springer
    Annals of hematology 69 (1994), S. 11-15 
    Details
    ISSN: 1432-0584
    Keywords: Acute nonlymphocytic leukemia ; Adult patients
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Between May 1985 and November 1988, 143 adult patients with previously untreated acute nonlymphocytic leukemia were randomized to receive mitoxantrone and cytarabine (MTT+Ara-C) or daunomycin and cytarabine (DNM+Ara-C) in order to compare the efficacy and acute and chronic toxicities. Therapy consisted of 3 days of MTT 12 mg/m2/i.v. or DNM 45 mg/m2/i.v.; both groups received Ara-C 100 mg/m2 daily by continuous infusion (CI) for 7 days. Those who failed to achieve a complete remission after one induction course received a second induction course for 2 and 5 days at the same doses. All the patients who achieved complete remission received two consolidations of 2 days of MTT or DNM and 5 days of Ara-C in CI at the same dose as for induction. Of the 72 patients on MTT+Ara-C, 38 (53%) achieved complete remission, compared with 29 (43%) of 67 treated with DNM+Ara-C. Three and 5 patients had partial remission, 7 and 18 failed to respond, 24 and 15 died in the first 21 days of induction, of those treated with MTT+Ara-C or DNM+Ara-C, respectively (p=0.34). Median duration of complete remission and survival was 185 and 103 days or 165 and 160 days, respectively (p=0.85). More early deaths were observed with MTT+Ara-C due to greater myelosuppression, and a higher incidence of failure with DNM+Ara-C. No significant differences between treatment groups were observed in 21 categories of adverse events. The results demonstrate similar incidence of complete response, length of duration of complete remission, overall survival, and toxicity with MTT+Ara-C and DNM+Ara-C.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01757342
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  • 8
    Electronic Resource
    Electronic Resource
    Biotransformation of a dietary sesterterpenoid in the Mediterranean nudibranchHypselodoris orsini (1993)
    Springer
    Cellular and molecular life sciences 49 (1993), S. 582-586 
    Details
    ISSN: 1420-9071
    Keywords: Nudibranch ; sponge ; Cacospongia mollior ; Hypselodoris orsini ; sesterterpenoids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The metabolic relationship between the marine molluscHypselodoris orsini and the spongeCacospongia mollior has been reinvestigated. The predator-prey association has been confirmed even though the metabolic patterns of the two invertebrates are substantially different. Most probably the nudibranch converts the main sponge metabolite, the sesterterpenoid scalaradial (1), into a less oxygenated related metabolite, deoxoscalarin (4), followed by a second chemical transformation leading to a new sesterterpenoid, 6-keto-deoxoscalarin (5) which is selectively compartmentalized into some dorsal glands, mantle dermal formations (MDFs), strategically distributed near the gills. 6-keto-deoxoscalarin (5) has been characterized by 1D and 2D NMR methods. Finally, the unusual association of some Chromodorididae molluscs with sponges containing sesterterpenoids suggests a further analysis of their taxonomical collocation is required.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01955168
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  • 9
    Electronic Resource
    Electronic Resource
    A histological and chemical study of the cerata of the opisthobranch molluscTethys fimbria (1991)
    Springer
    Marine biology 111 (1991), S. 353-358 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Tethys fimbria is a poorly studied nudibranch that, recently, has been shown to possess large amounts of unusual prostaglandin (PG) derivatives. The cerata ofT. fimbria collected in the Bay of Naples (Italy) between November 1990 and January 1991 were submitted to histological analysis. This revealed the presence of both longitudinal and transverse smooth muscle fibres together with multicellular defensive glands, responsible for the typical spontaneous contractions of the cerata and for the extrusion of a hyaline secretion, respectively. A role forT. fimbria cerata in mollusc defense behaviour is suggested. Chemical analysis of the cerata led to the isolation of high levels of prostaglandin free acids (PGs) and of PG-1,15-lactones of the E, A and F series, whereas the secretion contained only PG-1,15-lactones of the E and A series. The latter were found to be toxic to mosquito fish at concentrations ranging between 1 and 10 µg ml−1, whereas PG free acids and PG-1,15-lactones of the F series were not toxic. The possibility that PGE- and PGA-1.15-lactones areT. fimbria defense allomones is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01319406
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  • 10
    Electronic Resource
    Electronic Resource
    Anatomical and ultrastructural studies of chemical defence in the sponge Dysidea fragilis (1998)
    Springer
    Marine biology 131 (1998), S. 639-645 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The marine sponge Dysidea fragilis from El Mar Menor, a hypersaline coastal lagoon (Murcia, Spain), contains the furanosesquiterpenoid ent-furodysinin as the major secondary metabolite. D. fragilis emits a defensive white fluid when it is disturbed. Electron micrographs of this fluid revealed intact vesiculated cells together with other amorphous material. Dissociated cells are more rounded in shape but maintain the same ultrastructural features as cells observed in ultra-thin sections of the whole sponge. The defensive secretion is composed mainly of sponge cells with abundant light vesicles. Sometimes these light vesicles appear to open into the intercellular space; this correlates with surface blebs on these cells observed under scanning electron microscopy. The intracellular location of ent-furodysinin was confirmed by Erlich staining. In laboratory assays, we examined the role of ent-furodysinin as a feeding deterrent to generalist fish predators. It was isolated from D. fragilis and incorporated into a carrageenan-based artificial diet. The addition of ent-furodysinin to the artificial diet reduced feeding by the fish Thalassoma pavo. Similarly, fish did not feed on artificial diet above which defensive secretion of D. fragilis had been ejected with a small syringe.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002270050356
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