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  • 11
    Electronic Resource
    Electronic Resource
    Crystallization and preliminary X-ray studies on the trypsin inhibitor I-2 from wheat germ and its complex with trypsin (1993)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 49 (1993), S. 594-596 
    Details
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: A Bowman–Birk type trypsin inhibitor I-2, Mr = 14 000, 123 amino-acid residues, isolated from wheat germ, and its complex with trypsin have been crystallized. For I-2 two morphologically different crystal forms were obtained. Crystal form 1 is tetragonal, P4122 or P4322, with a = 55.45 (2), c = 129.1 (2) Å and V = 3.97 (2) × 105 Å3. The crystals diffract X-rays very anisotropically, to less than 6 Å resolution normal to the c* direction, but up to 3 Å resolution in the other directions. Crystal form 2 is monoclinic, space group C2. The cell parameters show significant variation even for crystals in the same batch. The median parameters are: a = 83.9, b = 41.5, c = 45.7 Å, β = 95.9° and V = 1.58 × 105 Å3. The diffraction pattern is isotropic and reflections up to 2.2 Å resolution were observed. The crystals of the complex between bovine trypsin and I-2 (2:1) belong to the orthorhombic space group P212121 with a = 73.49 (2), b = 120.56 (3), c = 70.04 (2) Å and V = 6.206 (5) × 105 Å3. The crystals diffract up to 2.3 Å resolution, and contain one complex of 60 100 Da in an asymmetric unit.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0907444993006134
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  • 12
    Electronic Resource
    Electronic Resource
    Invertebrate neuropeptides: Their localization, structure and function (1992)
    Springer
    Cellular and molecular life sciences 48 (1992), S. 423-424 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01928159
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  • 13
    Electronic Resource
    Electronic Resource
    Tissue plasminogen activator (t-PA) production by human fibroblasts using a bioreactor with t-PA adsorption column (1991)
    Springer
    Bioprocess and biosystems engineering 7 (1991), S. 137-140 
    Details
    ISSN: 1432-0797
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract Production of t-PA by human embryonic lung fibroblasts, IMR-90 cells, is regulated by negative feedback control. The increase in the concentration of the extracellular t-PA lead to a reduction of the production. Therefore, we investigated the application of t-PA adsorption column to ceramic bed reactor to promote t-PA production. Amberlite XAD-8 was selected out as an adsorbent, because it is autoclavable and can adsorb 32,000 IU of t-PA per g wet gel. The t-PA adsorption column was located in the medium recirculation line to the vessel. On the other hand, medium was recirculated between the ceramic bed reactor and the vessel using another flow line. The bioreactor system with the adsorption column was about 2.5 times higher with the resulting cumulative t-PA than that without the adsorption column.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00369425
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  • 14
    Electronic Resource
    Electronic Resource
    Development of Gas-Atomized Magnetic Tools (2005)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 291-292 (Aug. 2005), p. 287-290 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The deficiency in the variety of available magnetic abrasive results in a narrow range of finishing performance. To break through this difficulty, this research developed iron-based gas-atomized magnetic tools. The magnetic tool has a spherical shape and micro-crevices on the surface. The micro-crevices perform the role of cutting instead of the edges of the existing magnetic abrasive, thereby achieving abrasive-less finishing. This paper studies the finishing performance ofthe developed magnetic tool. Compared to the existing magnetic abrasive, this magnetic tool shows more efficient finishing performance in the internal finishing of SUS304 stainless steel tubes used for sanitary piping systems
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/49/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.291-292.287.pdf
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  • 15
    Electronic Resource
    Electronic Resource
    Particle Impact Damage in Silicon Carbide (1991)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 51-52 (Jan. 1991), p. 167-172 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/58/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.51-52.167.pdf
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  • 16
    Electronic Resource
    Electronic Resource
    Photorefractive properties of Cr-doped strontium-barium niobate at 514.5 nm and 632.8 nm: A comparative study (1994)
    Springer
    Applied physics 59 (1994), S. 579-582 
    Details
    ISSN: 1432-0630
    Keywords: 42.65 ; 42.70 ; 72.40
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Two-beam coupling gain and speed of a Cr-doped strontium-barium niobate single crystal at 514.5 nm and 632.8 nm are measured to compare photorefractive origins and responses. The same single deep center and single carriers are found to be responsible for the observed photorefractivities at both wavelengths. Self-pumped phase-conjugate reflectivities are also measured at both wavelengths.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00331915
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  • 17
    Electronic Resource
    Electronic Resource
    Atomic Mechanisms of Grain Boundary Motion (2005)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 502 (Dec. 2005), p. 157-162 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: We present results of atomistic computer simulations of spontaneous and stress-induced grain boundary (GB) migration in copper. Several symmetrical tilt GBs have been studied using the embedded-atom method and molecular dynamics. The GBs are observed to spontaneously migrate in a random manner. This spontaneous GB motion is always accompanied by relative translations of the grains parallel to the GB plane. Furthermore, external shear stresses applied parallel to the GB and normal to the tilt axis induce GB migration. Strong coupling is observed between the normal GB velocity vn and the grain translation rate v||. The mechanism of GB motion is established to be local lattice rotation within the GB core that does not involve any GB diffusion or sliding. The coupling constant between vn and v|| predicted within a simple geometric model accurately matches the molecular dynamics observations
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/11/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.502.157.pdf
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  • 18
    Electronic Resource
    Electronic Resource
    Unruptured aneurysms associated with ischaemic cerebrovascular diseases. Surgical indication (1993)
    Springer
    Acta neurochirurgica 124 (1993), S. 71-78 
    Details
    ISSN: 0942-0940
    Keywords: Ischaemic cerebrovascular disease ; unruptured intraeranial aneurysm ; surgical indications ; results ; subarachnoid haemorrhage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Out of 3435 patients with ischaemic cerebrovascular disease 2540 cases were investigated using cerebral angiography. In 127 of them (5%) aneurysms were found, but without clinical evidence of subarachnoid haemorrhage (SAH). 45 cases were operated upon and 82 were treated conservatively. Five of these 82 cases (6%) suffered from SAH 3 months to 10 years (mean interval 5,6 years) after the angiographic diagnosis. Four of these 5 patients with SAH died. Among the 45 surgical cases follow-up was uneventful in 29 (64%). The other 16 cases postoperatively showed neurological deterioration (36%), which was transient in 6 but with only minor improvement in 10. Of these 10 cases 2 died from cerebral infarction related to intra-operative temporary vascular occlusion respectively myocardial infarction. Thus surgical mortality was 4% and permanent morbidity 18%. Causes of postoperative neurological deterioration were partly related to general arteriosclerotic changes and special fragility of the ischaemic brain, and partly to operative technique (excessive brain retraction, damage to cortical veins, occlusion of major vessels or damage to perforators, temporary artery occlusion). Apparently in cases with ischaemic cerebrovascular diseases operative procedures, which in other cases as a rule are well tolerated, may produce harmful effects. Therefore, in these cases, the indication for operative treatment of so far silent aneurysms should be restricted to patients who are in good general condition with longer life expectancy as far as the vascular disease is concerned, and without major neurological deficit. Furthermore, the operative technique should be especially gentle and atraumatic.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401125
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  • 19
    Electronic Resource
    Electronic Resource
    The basal interhemispheric approach for acute anterior communicating aneurysms (1992)
    Springer
    Acta neurochirurgica 118 (1992), S. 91-97 
    Details
    ISSN: 0942-0940
    Keywords: Anterior communicating artery ; aneurysm ; early surgery ; operative approach
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We reviewed the surgical outcome in 85 patients with ruptured anterior communicating artery (ACoA) aneurysms, who were operated on within 72 hours of onset via a basal interhemispheric (BIH) approach (Group 1, N=48), or an anterior interhemispheric (AIH) approach (Group 2, N=37). The age, sex ratio and pre-operative grade (Gr) were similar for both groups. The outcome at the time of discharge was as follows for group 1: excellent or good 88%; fair, 6%; vegetative state, 2% and death 4%. For group 2, it was: excellent or good 78%; fair, 16%; vegetative state, 3%; and death, 3%. A significant correlation between admission grade and outcome was found in both groups. The outcome in group 1 was better than in group 2 for patients with a Glasgow Outcome Scale (GOS) better than fair (p 〈 0.07). No patient in group 1 had postoperative anosmia, but nine patients in group 2 became anosmic. The total number of complications was also significantly less in group 1. Our overall mortality rate was 4%. In conclusion, the BIH approach was more beneficial for treating acute ACoA aneurysm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401292
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  • 20
    Electronic Resource
    Electronic Resource
    S18.15 The key enzyme which regulates CMP-N-acetylneuraminic acid hydroxylation is a novel protein (1993)
    Springer
    Glycoconjugate journal 10 (1993), S. 331-331 
    Details
    ISSN: 1573-4986
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01210149
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