Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 2005-2009
  • 1980-1984  (2)
  • Isovaline  (1)
  • Lipid bilayers  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Alamethicin pore formation: Voltage-dependent flip-flop of α-helix dipoles (1983)
    Springer
    European biophysics journal 9 (1983), S. 181-191 
    Details
    ISSN: 1432-1017
    Keywords: Alamethicin pore ; Voltage-dependent conductance ; α-helical structure ; Dipole moment ; Lipid bilayers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The voltage-dependency of alamethicin pore formation is explained by a flip-flop gating mechanism of single alamethicin molecules. The energetically preferred aggregate structure is changed from antiparallel to parallel molecule orientation by membrane voltage application. The electrical field is sensed by the permanent dipole of the α-helical molecule part which spans the hydrophobic membrane core. Ion conducting pore and pore states result from electrostatic repulsion of a varying number of parallel dipoles which arrange circularly. This model is consistent with published data and with two additional experimental facts, that pore state distributions are ionic strength dependent and pore state conductances depend on ionic current direction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00537815
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Gas chromatographic determination of the configuration of isovaline in antiamoebin, samarosporin (emerimicin IV), stilbellin, suzukacillins and trichotoxins (1980)
    Springer
    Chromatographia 13 (1980), S. 209-214 
    Details
    ISSN: 1612-1112
    Keywords: Configuration ; Chiral phases ; Gas chromatography ; Isovaline
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The D-(resp. R) configuration of isovaline (=2-ethylalanine) was proved for the peptide antibiotics antiamoebin, Tü 165 (CBS 382.62), stilbellin, samarosporin (=emerimicin IV), suzukacillin B (A), trichotoxin A-40 and A-50. This contradicts the previously reported L-configuration for isovaline in antiamoebin and emerimicin IV. The configuration was determined by GC of the N-trifluoroacetyl-isovaline n-propyl ester on glass capillary columns coated with the chiral stationary phase N-propionyl-L-valine tert.-butylamide polysiloxane (Chirasil Val). The D-configuration of the isovaline from trichotoxin A-40 was also established independently using GC of N-pentafluoro-propionyl-isovaline (+)-3-methyl-2-butyl esters on glass capillary columns coated with OV 17.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02261873
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...